HEALTH CONDITION

Bullous pemphigoid

Bullous pemphigoid is a rare skin condition that mainly affects people over the age of 60. It may last a few years and can be serious, but treatment helps.

Symptoms of bullous pemphigoid

Bullous pemphigoid usually starts with an itchy, raised rash on the skin, usually the backs of the knees, insides of the armpits and elbows, hands, feet or tummy. The sore, itchy patches look red or pink on white skin and dark reddish-brown on brown or black skin. Credit: DR P. MARAZZI/SCIENCE PHOTO LIBRARY https://www.sciencephoto.com/media/711904/view It can affect large areas of the body or limbs. Credit: ISM/SCIENCE PHOTO LIBRARY https://www.sciencephoto.com/media/880176/view After a few weeks, small blisters may appear. Credit: DR P. MARAZZI/SCIENCE PHOTO LIBRARY https://www.sciencephoto.com/media/711900/view The blisters can grow quite big and may contain blood. Credit: DR P. MARAZZI/SCIENCE PHOTO LIBRARY https://www.sciencephoto.com/media/260961/view Some people may also get blisters in their mouth, which can cause problems swallowing (dysphagia) . Not everyone gets blisters. If you do, they may keep coming and going for months or years. Bullous pemphigoid eventually goes away on its own.

Treatment for bullous pemphigoid

If a GP thinks you have bullous pemphigoid, they may refer you to a specialist for tests and treatment. The main treatments for bullous pemphigoid are: steroid creams steroid tablets antibiotics Treatment can help your skin heal, stop new patches or blisters appearing, and lower the chances of your skin getting infected. Your skin should eventually heal without scarring, but it might be a bit darker than it was before. Important Do not burst your blisters yourself unless you have been shown how to by a nurse. Your skin might get infected.

Complications of bullous pemphigoid

Bullous pemphigoid can sometimes cause serious problems and may be life threatening to people at higher risk of complications. The main risks are: skin infections, which can be very serious if they get deeper into your body ( sepsis ) side effects of steroid treatment, such as high blood pressure, weakened bones and a higher chance of getting infections Steroids will be used as little as possible, and at the lowest possible dose, to help avoid side effects. It's important to go to check-ups with your doctor so problems can be found and treated early.

Causes of bullous pemphigoid

Bullous pemphigoid is caused by a problem with the immune system, the body's defence against infection. Instead of attacking germs, it attacks and damages the skin. It's not always clear why this happens, although certain things may trigger it. These include: certain medicines sunburn surgery burns

Source: NHS, last reviewed 06 February 2025. Contains public sector information licensed under the Open Government Licence v3.0.

This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.