GENERIC
Bicarbonate Component [HCO3 Hemodialysis Solution]
Indications
G-Haemodialysis B [HCO3 Hemodialysis Solution] solution is indicated in renal failure, Chronic renal failure and Haemodialysis. G-Haemodialysis B serves a crucial biochemical role in the physiological pH buffering system.
Pharmacology
Sodium chloride is the major extracellular cation. It is important in electrolyte and fluid balance, osmotic pressure control and water distribution as it restores sodium ions. It is used as a source of electrolytes and water for hydration, treatment of metabolic acidosis, priming solution in haemodialysis and treatment of hyperosmolar diabetes. It is also used as diluents for infusion of compatible drug additives. Sodium bicarbonate raises blood and urinary pH by dissociation to provide bicarbonate ions, which neutralises the hydrogen ion concentration. It also neutralises gastric acid via production of carbon dioxide.
Dosage and administration
Acidic component & Bicarbonate Component should be used in the dilution ratio of-
- Acidic component: 1.00 Volume
- Bicarbonate Component: 1.83 Volume
- Purified Water: 34.00 Volume
Interactions
Sodium bicarbonate: Increases toxicity of amphetamines, ephedrine, pseudoephedrine, flecainide, quinidine and quinine. Decreases effects of lithium, chlorpropamide and salicylates due to increased clearance. May affect the absorption of certain drugs due to raised intra-gastric pH. Sodium chloride: May affect serum concentrations of lithium.
Contraindications
Known hypersensitivity to any of the ingredients of this preparation.
Precautions and warnings
G-Haemodialysis B needs to be used with Acidic component (not to be used alone).
Before use, the mixed solution must be diluted with
highly purified water.
Close the container tightly immediately after use.
Discard solution in case of visible solid particles inside.
Discard solution after 96 hours of first opening.
Storage
Keep out of reach of children. Not for Injection. Store below 30°C.
Clinical information is taken from the most complete brand listing (G-Haemodialysis B); it applies to the active ingredient.
Brands of Bicarbonate Component [HCO3 Hemodialysis Solution]
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Dialyte-B | Popular Pharmaceuticals Ltd. | Dialysis Solution | – | Not listed |
| 2 | G-Haemodialysis B | Gonoshasthaya Pharma Ltd. | Dialysis Solution | – | Not listed |
| 3 | Hemosol-B | Square Pharmaceuticals PLC | Dialysis Solution | – | Not listed |
| 4 | Renalaid-B | Labaid Pharma Ltd. | Dialysis Solution | – | Not listed |
| 5 | Renal Care B | Greenland Pharmaceuticals Ltd. | Dialysis Solution | – | Not listed |
| 6 | Renolyte-B | Guardian Healthcare Ltd. | Dialysis Solution | – | Not listed |
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.