GENERIC

Chloroxylenol

Indications

Disinfectant for-

skin and gloved hands

obstetrics, antiseptic lubricant for vaginal examinations and on forceps

for hand antisepsis.

  • First aid to help prevent infection in minor-
  • cuts
  • scrapes
  • burns

Pharmacology

As a phenol antiseptic, it is believed that the hydroxyl -OH groups of the chloroxylenol molecule binds to certain proteins on the cell membrane of bacteria, and disrupts the membrane so as to allow the contents of the bacterial cell to leak out. This allows chloroxylenol to enter the bacterial cell to bind further with more proteins and enzymes to disable the cell's functioning. At particularly high concentrations of chloroxylenol, the protein and nucleic acid content of targeted bacterial cells become coagulated and cease to function, leading to rapid cell death.

Dosage and administration

  • Dilute 1 tablespoonful (15mL) in 10 oz. (300 mL) of water
  • Clean the affected area
  • Apply to affected area and cover with gauze or bandage

Do not use undiluted product.

Interactions

There are no known drug interactions and none well documented.

Contraindications

Hypersensitivity

Side effects

Skin sensitivity; irritation of conjunctiva, mucosal irritation; reversible brown staining of the teeth; tongue discoloration and burning sensation; transient taste disturbance; parotid gland swelling.

Precautions and warnings

For external use only Do not use-

  • in the eyes
  • over large areas of the body
  • Ask a doctor before use if you have-
  • deep wounds or puncture wounds
  • animal bites
  • serious burns
  • Stop use and ask a doctor if-

irritation, sensitization, or allergic reaction occurs. These may be signs of a serious condition.

condition gets worse or lasts more than one week

Storage

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. Do not induce vomiting.

Clinical information is taken from the most complete brand listing (Dettol); it applies to the active ingredient.

Brands of Chloroxylenol

Brands of Chloroxylenol
#BrandCompanyFormStrengthPrice
1DettolReckitt & Benckiser Ltd.Liquid4.8% w/vNot listed
2DextolPharmik Laboratories Ltd.Liquid4.8% w/vNot listed

This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.