GENERIC
Cyclizine Hydrochloride
Indications
Travelit is indicated in-
Motion sickness: Travelit is indicated for the prevention and treatment of nausea and vomiting.
PONV (Postoperative nausea & vomiting)
Meniere's disease etc.
Pharmacology
Cyclizine Hydrochloride is an US FDA approved antihistaminic antiemetic drug. It possesses anticholinergic and antiemetic properties. It reduces excitability of inner ear labyrinth and acts directly on vomiting (Emetic) centre in the brain stem.
Dosage and administration
Motion Sickness:
Adults : 1 Tablet (50 mg)
Children: (6 years & above) : 1/2 Tablet (25 mg). 1 tablet should be taken at least 30 minutes before journey (before or after meal), repeat 1 tablet if journey is more than 6 hours
Postoperative Nausea & Vomiting, Meniere's disease:
Adults : 1 Tablet (50 mg) every 6-8 hours daily
Children: (6 years & above) : 1/2 Tablet (25 mg) every 6-8 hours daily
Interactions
Travelit may have additive effects with alcohol and other CNS depressants e.g. hypnotics, tranquillisers, anaesthetics, antipsychotics & barbiturates. It enhances the soporific effect of pethidine & also counteract the haemodynamic benefits of opioid analgesics.
Contraindications
Hypersensitivity to the active substance or to the other excipients. Cyclizine is contraindicated in the presence of acute alcohol intoxication. The anti-emetic properties of cyclizine may increase the toxicity of alcohol.
Side effects
Itching or skin rashes, swelling of the face, lips or throat, difficulty in breathing or wheeziness.
Pregnancy and lactation
It is safe in pregnancy according to TGA category "A" & US FDA category "B". Cyclizine Hydrochloride is excreted in milk. So in case of lactating mother, precaution should be taken before taking Cyclizine Hydrochloride.
Precautions and warnings
Travelit should be used with caution and appropriate monitoring in patients with glaucoma, urinary retention, obstructive disease of the gastrointestinal tract, hepatic disease, hypertension, epilepsy, severe heart failure.
Storage
Store below 30°C temperature.Protected from light & moisture.Keep all the medicines out of the reach of children.
Clinical information is taken from the most complete brand listing (Travelit); it applies to the active ingredient.
Brands of Cyclizine Hydrochloride
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Travelit | Sharif Pharmaceuticals Ltd. | Tablet | 50 mg | Not listed |
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.