GENERIC
Inactivated Hepatitis A vaccine
Indications
The vaccine is indicated for the active immunization of adults and children from 12 months of age against infection caused by Hepatitis A virus.
Pharmacology
The hepatitis A virus belongs to the picornavirus family. It is one of several hepatitis viruses that cause systemic disease with pathology in the liver. The incubation period for hepatitis A averages 28 days (range: 15 to 50 days). The course of hepatitis A infection is extremely variable, ranging from asymptomatic infection to icteric hepatitis and death. The presence of antibodies to HAV confers protection against hepatitis A infection. However, the lowest titer needed to confer protection has not been determined.
Dosage and administration
Hepatitis A vaccine should be given intramuscularly only. Do not inject it intravenously. The primary immunization consists of two doses, the first dose is at the selected date and the second dose will be at 6 months later. Children 12 months to 15 years: The recommended dose is 0.5 ml
First dose : At the elected date
Second dose : 6 months after the first dose
Children 16 years and above: The recommended dose is 1 ml
First dose : At the elected date
Second dose : 6 months after the first dose
Contraindications
People who are allergic to any component of the vaccine. People who suffer from serious diseases, fever, and any immune disease
Side effects
Reactions at the site of injection are common but can be recovered within 72 hours without any treatment. Some of the mild and temporary adverse reactions are: pain and redness at the site of injection, fever after vaccination.
Pregnancy and lactation
The vaccine should be given to a pregnant woman only if clearly needed. The vaccine should be used with caution for lactating women.
Precautions and warnings
Shake well before use
The product should be used with caution for people who or whose family has the history of convulsion or epilepsy, chronic diseases and allergic symptoms
Do not use the product if any crack of the container, foreign particulate matter, or out of expiry date
PrevaHAV (For adult) should be used immediately after opening
Adrenaline and other first aid medicines should be prepared at the vaccination place in serious allergic reaction. The people after vaccination should remain under medical supervision for 30 minutes
The vaccine must not be frozen
Storage
Keep out of the reach and sight of children Store and transport at 2°C to 8°C. Protect from light
Clinical information is taken from the most complete brand listing (PrevaHAV (For adult)); it applies to the active ingredient.
Brands of Inactivated Hepatitis A vaccine
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Avaxim (For child) | Synovia Pharma PLC. | SC Injection | 80 unit/0.5 ml | Not listed |
| 2 | PrevaHAV (For adult) | Incepta Pharmaceuticals Ltd. | SC Injection | 500 unit/1 ml | Not listed |
| 3 | PrevaHAV (For child) | Incepta Pharmaceuticals Ltd. | SC Injection | 250 unit/0.5 ml | Not listed |
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.