GENERIC
Ravuconazole
Indications
Ravu capsule is indicated for the treatment of Onychomycosis.
Pharmacology
Fosravuconazole L-lysine ethanolate is a prodrug of Ravuconazole, a novel triazole antifungal agent, exerting broad and potent antifungal activity. It shows antimycotic effects by inhibiting the biosynthesis of ergosterol, which is a cellular membrane component of fungi. Ravuconazole is structurally more similar to fluconazole and voriconazole, containing a thiazole instead of a second triazole. It is usually used to treat Onychomycosis. Ravuconazole is highly active against all Aspergillus species (including A. fumigatus & A. flavus isolates), Candida spp., Cryptococcus neoformans & other yeasts, including fluconazole-resistant isolates.
Dosage and administration
The usual adult dosage is 1 capsule (100 mg as Ravuconazole) administered orally once daily for a period of 12 weeks.
Interactions
The therapeutic efficacy of Ravu can be increased when used in combination with Amiodarone, Amlodipine, Bepridil, Cinnarizine, Clevidipine & Carvedilol. The therapeutic efficacy of Acenocoumarol can be increased when used in combination with Ravu. Cimetidine, Calcium carbonate, Almasilate, Aluminium phosphate, Aluminum hydroxide & Asenapine can cause a decrease in the absorption of Ravu resulting in a reduced serum concentration and potentially a decrease in efficacy.
Contraindications
Do not use in cases of known sensitivity (specially generalized allergic reaction) to any of the ingredients.
Side effects
The most commonly reported adverse reactions include stomach discomfort, constipation and angular cheilitis. If any of these symptoms occur, consult with your doctor. The symptoms described below are rarely seen as initial symptoms of the adverse reactions. If any of these symptoms occur, stop taking this medicine and see your doctor immediately:
loss of appetite, nausea, jaundice [liver dysfunction]
Round or oval red rash, fever, joint pain [erythema multiforme]
Pregnancy and lactation
If anyone is capable of becoming pregnant, be sure to use birth control while taking this medicine and for at least 3 months after discontinuing this medicine.
Precautions and warnings
Trim the lesioned nail with a file or nail clipper as necessary. If anyone is capable of becoming pregnant, be sure to use birth control while taking this medicine and for at least 3 months after discontinuing this medicine.
Storage
Store below 30°C, in a dry place. Keep all medicines out of reach of children.
Clinical information is taken from the most complete brand listing (Ravu); it applies to the active ingredient.
Brands of Ravuconazole
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Ravu | Square Pharmaceuticals PLC | Capsule | 100 mg | ৳ 300.00per unit |
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.