17-OH progesterone

A blood sample is needed. Most of the time, blood is drawn from a vein located on the inside of the elbow or the back of the hand. In infants or young children, a sharp tool called a lancet may be used to puncture the skin. The blood collects in a small glass tube called a pipette, or onto a slide or test strip. A…

Many medicines can interfere with blood test results. Your health care provider will tell you if you need to stop taking any medicines before you have this test. Do not stop or change your medicines without talking to your provider first.

You may feel slight pain or a sting when the needle is inserted. You may also feel some throbbing at the site after the blood is drawn.

The main use of this test is to check infants for an inherited disorder that affects the adrenal gland, called congenital adrenal hyperplasia (CAH). It is often done on infants who are born with outer genitals that do not clearly look like those of a boy or a girl. This test is also used to identify people who develop…

Normal and abnormal values differ for babies born with low birth weight. In general, normal results are as follows: Babies more than 24 hours old - less than 400 to 600 nanograms per deciliter (ng/dL) or 12.12 to 18.18 nanomoles per liter (nmol/L) Children before puberty around 100 ng/dL or 3.03 nmol/L Adults - less…

A high level of 17-OH progesterone may be due to: Tumors of the adrenal gland Congenital adrenal hyperplasia (CAH) In infants with CAH, the 17-OHP level ranges from 2,000 to 40,000 ng/dL or 60.6 to 1212 nmol/L. In adults, a level greater than 200 ng/dL or 6.06 nmol/L may be due to nonclassical adrenal hyperplasia.

Your provider may suggest an ACTH test if 17-OH progesterone level is between 200 to 800 ng/dL or 6.06 to 24.24 nmol/L.

Chan Y-M, Hannema SE, Achermann JC, Hughes IA. Disorders of sex development. In: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Textbook of Endocrinology. 14th ed. Philadelphia, PA; Elsevier; 2020:chap: 24. Guber HA, Oprea M, Rusell YX. Evaluation of endocrine function. In: McPherson RA, Pincus…