LAB TEST
Alpha fetoprotein
Alpha fetoprotein (AFP) is a protein produced by the liver and yolk sac of a developing baby during pregnancy. AFP levels go down soon after birth. It is likely that AFP has no normal function in adults. A test can be done to measure the amount of AFP in your blood.
How the Test is Performed
A blood sample is needed. Most of the time, blood is typically drawn from a vein located on the inside of the elbow or the back of the hand.
How to Prepare for the Test
You do not need to take any special steps to prepare.
How the Test will Feel
You may feel slight pain or a sting when the needle is inserted. You may also feel some throbbing at the site after the blood is drawn.
Why the Test is Performed
Your health care provider may order this test to: Screen for problems in the baby during pregnancy. (The test is done as part of a larger set of blood tests called quadruple screen .) Diagnose certain liver disorders. Screen for and monitor some cancers.
Normal Results
The normal values in males or nonpregnant females is generally less than 40 micrograms/liter. The examples above are common measurements for results of these tests. Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider…
What Abnormal Results Mean
Greater than normal levels of AFP may be due to: Cancer in testes , ovaries, biliary (liver secretion) tract, stomach, or pancreas Cirrhosis of the liver Liver cancer Malignant teratoma Recovery from hepatitis Problems during pregnancy
References
Driscoll DA, Simpson JL. Genetic screening and diagnosis. In: Landon MB, Galan HL, Jauniaux ERM, et al, eds. Gabbe's Obstetrics: Normal and Problem Pregnancies . 8th ed. Philadelphia, PA: Elsevier; 2021:chap 10. Dugoff L, Wapner RJ. Prenatal diagnosis of congenital disorders. In: Lockwood CJ, Copel JA, Dugoff L et al,…
This is a summary. Read the full article at www.ucsfbenioffchildrens.org (reviewed 23/08/2023).
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.