LAB TEST

Blood differential test

The blood differential test measures the percentage of each type of white blood cell (WBC) that you have in your blood. It also reveals if there are any abnormal or immature cells.

How the Test is Performed

A blood sample is needed. A laboratory specialist takes a drop of blood from your sample and smears it onto a glass slide. The smear is stained with a special dye, which helps tell the difference between various types of white blood cells. Five types of white blood cells, also called leukocytes, normally appear in the…

How to Prepare for the Test

No special preparation is necessary.

How the Test will Feel

When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or slight bruising. This soon goes away.

Why the Test is Performed

This test is done to diagnose an infection, anemia , or leukemia . It may also be used to monitor one of these conditions or to see if treatment is working.

Normal Results

The different types of white blood cells are given as a percentage of all white cells: Neutrophils: 40% to 60% Lymphocytes: 20% to 40% Monocytes: 2% to 8% Eosinophils: 1% to 4% Basophils: 0.5% to 1% Band (young neutrophil): 0% to 3%

What Abnormal Results Mean

Any infection or acute stress increases your number of white blood cells. High white blood cell counts may be due to inflammation, an immune response, or blood diseases such as leukemia. Abnormal or immature white blood cells may indicate leukemia or bone marrow invasion by cancer or infection. It is important to…

Risks

There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another, and from one side of the body to the other. Taking blood from some people may be more difficult than from others. Other risks associated with having blood drawn are slight, but may include: Excessive…

References

Bain BJ. The peripheral blood smear. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 26th ed. Philadelphia, PA: Elsevier; 2020:chap 148. Nasr MR, Hutchison RE. Leukocytic disorders. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods . 24th ed. Philadelphia, PA:…

This is a summary. Read the full article at www.ucsfbenioffchildrens.org (reviewed 02/02/2023).

This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.