LAB TEST

CA-125 blood test

The CA-125 blood test measures the level of the protein CA-125 in the blood.

How the Test is Performed

A blood sample is needed.

How to Prepare for the Test

No preparation is necessary.

How the Test will Feel

When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.

Why the Test is Performed

CA-125 is a protein that is found more in ovarian cancer cells than in other cells. This blood test is often used to monitor women who have been diagnosed with ovarian cancer . The test is useful if the CA-125 level was high when the cancer was first diagnosed. In these cases, measuring the CA-125 over time is a good…

Normal Results

A level above 35 U/mL is considered abnormal. Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your doctor about the meaning of your specific test results.

What Abnormal Results Mean

In a woman who has ovarian cancer, a rise in CA-125 usually means that the disease has progressed or come back (recurred). A decrease in CA-125 usually means the disease is responding to current treatment. In a woman who has not been diagnosed with ovarian cancer, a rise in CA-125 may mean a number of things. While it…

Risks

There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking a blood sample from some people may be more difficult than from others. Other risks associated with having blood drawn are slight, but may include:…

References

Coleman RL, Liu J, Matsuo K, Thaker PH, Westin SN, Sood AK. Carcinoma of the ovaries and fallopian tubes. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology . 6th ed. Philadelphia, PA: Elsevier; 2020:chap 86. Freund KM. Approach to women's health. In: Goldman L,…

This is a summary. Read the full article at www.ucsfbenioffchildrens.org (reviewed 16/10/2022).

This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.