LAB TEST

Cone biopsy

A cone biopsy (conization) is surgery to remove a sample of abnormal tissue from the cervix. The cervix is the lower part of the uterus (womb) that opens at the top of the vagina. Abnormal changes in the cells on the surface of the cervix is called cervical dysplasia .

How the Test is Performed

This procedure is done in the hospital or in a surgery center. During the procedure: You will be given general anesthesia (asleep and pain-free), or medicines to help you relax and feel sleepy. You will lie on a table and place your feet in stirrups to position your pelvis for exam. The health care provider will place…

How to Prepare for the Test

You may be asked to not eat or drink for 6 to 8 hours before the test.

How the Test will Feel

After the procedure, you may have some cramping or discomfort for about a week. For about 4 to 6 weeks avoid: Douching (douching should never be done) Sexual intercourse Using tampons For 2 to 3 weeks after the procedure, you may have discharge that is: Bloody Heavy Yellow-colored

Why the Test is Performed

Cone biopsy is done to detect cervical cancer or early changes that lead to cancer. A cone biopsy is done if a test called colposcopy cannot find the cause of an abnormal Pap smear. Cone biopsy may also be used to treat: Moderate to severe types of abnormal cell changes (called CIN II or CIN III) Very early stage…

Normal Results

A normal result means there are no precancerous or cancerous cells in the cervix.

What Abnormal Results Mean

Most often, abnormal results mean that there are precancerous or cancerous cells in the cervix. These changes are called cervical intraepithelial neoplasia (CIN). The changes are divided into 3 groups: CIN I -- mild dysplasia CIN II -- moderate to marked dysplasia CIN III -- severe dysplasia to carcinoma in situ…

Risks

Risks of cone biopsy include: Bleeding Incompetent cervix (which may lead to premature delivery) Infection Scarring of the cervix (which may cause painful periods, premature delivery, and difficulty getting pregnant) Damage to the bladder or rectum Cone biopsy may also make it hard for your provider to interpret…

References

Cohen PA, Jhingran A, Oaknin A, Denny L. Cervical cancer. Lancet . 2019;393(10167):169-182. PMID: 30638582 pubmed.ncbi.nlm.nih.gov/30638582/ . Salcedo MP, Phoolcharoen N, Schmeler KM. Intraepithelial neoplasia of the lower genital tract (cervix, vagina, vulva): etiology, screening, diagnosis, management. In:…

This is a summary. Read the full article at www.ucsfbenioffchildrens.org (reviewed 31/03/2024).

This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.