LAB TEST
CSF analysis
Cerebrospinal fluid (CSF) analysis is a group of laboratory tests that measure chemicals in the cerebrospinal fluid. CSF is a clear fluid that surrounds and protects the brain and spinal cord. The tests may look for proteins, sugar (glucose), and other substances.
How the Test is Performed
A sample of CSF is needed. A lumbar puncture , also called a spinal tap, is the most common way to collect this sample. Less common ways to take a fluid sample include: Cisternal puncture Removal of CSF from a tube that is already in the CSF, such as a shunt, ventricular drain, or pain pump Ventricular puncture After…
How to Prepare for the Test
Your provider will tell you how to prepare for lumbar puncture . Make sure to let them know all of the medicines you are taking in case any adjustment is needed.
Why the Test is Performed
Analysis of CSF can help detect certain conditions and diseases. All of the following can be, but are not always, measured in a sample of CSF: Antibodies and DNA of common viruses Bacteria (including that which causes syphilis, using a VDRL test ) Cell count Chloride Cryptococcal antigen Glucose Glutamine Lactate…
Normal Results
Normal results include: Antibodies and DNA of common viruses: None Bacteria: No bacteria grows in a lab culture Cancerous cells: No cancerous cells present Cell count: 0 to 5 white blood cells (all mononuclear) and 0 red blood cells Chloride: 110 to 125 mEq/L (110 to 125 mmol/L) Fungus: None Gamma globulin: 3% to 12%…
What Abnormal Results Mean
An abnormal CSF analysis result may be due to many different causes, including: Cancer Encephalitis (such as Herpes simplex, West Nile, and Eastern Equine Encephalitis virus) Hepatic encephalopathy High blood sugar (hyperglycemia) Infection Inflammation Reye syndrome Meningitis due to bacteria, fungus, tuberculosis,…
References
Euerle BD. Spinal puncture and cerebrospinal fluid examination. In: Roberts JR, Custalow CB, Thomsen TW, eds. Roberts and Hedges' Clinical Procedures in Emergency Medicine and Acute Care . 7th ed. Philadelphia, PA: Elsevier; 2019:chap 60. Rosenberg GA. Brain edema and disorders of cerebrospinal fluid circulation. In:…
This is a summary. Read the full article at www.ucsfbenioffchildrens.org (reviewed 29/04/2023).
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.