LAB TEST
Histocompatibility antigen test
A histocompatibility antigen blood test looks at proteins called human leukocyte antigens (HLAs). These are found on the surface of almost all cells in the human body. HLAs are found in large amounts on the surface of white blood cells. They help the immune system tell the difference between body tissue and substances that are not from your own body.
How the Test is Performed
Blood is drawn from a vein . You may feel slight pain or a sting when the needle is inserted. Afterward, there may be some throbbing.
How to Prepare for the Test
You do not need to prepare for this test.
Why the Test is Performed
The results from this test can be used to identify good matches for tissue grafts and organ transplants. These may include kidney transplant or bone marrow transplant . It may also be used to: Diagnose certain autoimmune disorders. Drug-induced hypersensitivity is an example. Determine relationships between children…
Normal Results
You have a small set of HLAs that are passed down from your parents. Children, on average, will have half of their HLAs match half of their mother's and half of their HLAs match half of their father's. It is unlikely that two unrelated people will have the same HLA makeup. However, identical twins may match each…
Risks
There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others. Other risks associated with having blood drawn are slight, but may include: Fainting…
References
Bray R, Sullivan C, Krummey S, Gebel HM. Human leukocyte antigen: the major histocompatibility complex of humans. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods . 24th ed. Philadelphia, PA: Elsevier; 2022:chap 50. Monos DS, Rajalingam R. The major histocompatibility…
This is a summary. Read the full article at www.ucsfbenioffchildrens.org (reviewed 24/01/2023).
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.