LAB TEST
Lymph node biopsy
A lymph node biopsy is the removal of lymph node tissue for examination under a microscope. The lymph nodes are small glands that make white blood cells (lymphocytes), which fight infection. Lymph nodes may trap the germs that are causing an infection. Cancer can spread to lymph nodes.
How the Test is Performed
A lymph node biopsy is often done in an operating room in a hospital or at an outpatient surgical center. The biopsy may be done in different ways. An open biopsy is surgery to remove all or part of the lymph node. This is usually done if there is a lymph node that can be felt on exam. This can be done with local…
How to Prepare for the Test
Tell your surgeon: If you are pregnant If you have any allergies to medicines If you have bleeding problems What medicines you are taking (including any supplements or herbal remedies) Your surgeon may ask you to: Stop taking any blood thinners, such as aspirin, heparin, warfarin (Coumadin), or clopidogrel (Plavix) as…
How the Test will Feel
When the local anesthetic is injected, you will feel a prick and a mild stinging. The biopsy site will be sore for a few days after the test. After an open or laparoscopic biopsy, the pain is usually mild and you can easily control it with an over-the-counter pain medicine. You may also notice some bruising or fluid…
Why the Test is Performed
The test is used to diagnose cancer, sarcoidosis , or an infection (such as tuberculosis): When you or your health care provider feel swollen lymph glands and they do not go away When abnormal lymph nodes are present on a mammogram , ultrasound, CT, or MRI scan For some people with cancer, such as breast cancer or…
Normal Results
If a lymph node biopsy does not show any signs of cancer, it is more likely that other lymph nodes nearby are also cancer-free. This information can help the provider decide about further tests and treatments.
What Abnormal Results Mean
Abnormal results may be due to many different conditions, from very mild infections to cancer. For example, enlarged lymph nodes may be due to: Cancers (breast, lung , oral ) HIV Cancer of the lymph tissue ( Hodgkin or non-Hodgkin lymphoma) Infection (tuberculosis, cat scratch disease ) Inflammation of lymph nodes and…
Risks
Lymph node biopsy may result in any of the following: Bleeding Infection (in rare cases, the wound may get infected and you may need to take antibiotics) Nerve injury if the biopsy is done on a lymph node close to nerves (the numbness usually goes away in a few months)
References
Dinulos JGH. Nevi and malignant melanoma. In: Dinulos JGH, ed. Habif's Clinical Dermatology . 7th ed. Philadelphia, PA: Elsevier; 2021:chap 22. National Cancer Institute website. Sentinel lymph node biopsy. www.cancer.gov/about-cancer/diagnosis-staging/staging/sentinel-node-biopsy-fact-sheet . Updated June 25, 2019.…
This is a summary. Read the full article at www.ucsfbenioffchildrens.org (reviewed 29/05/2024).
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.