LAB TEST

Methylene blue test

The methylene blue test is a test to determine the type or to treat methemoglobinemia , a blood disorder.

How the Test is Performed

The health care provider wraps a tight band or blood pressure cuff around your upper arm. The pressure causes veins below the area to fill with blood. The arm is cleaned with a germ killer (antiseptic). A needle is placed into your vein, usually near the inside of the elbow or back of the hand. A thin tube, called a…

How to Prepare for the Test

No special preparation is required for this test.

How the Test will Feel

When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or slight bruising. This soon goes away.

Why the Test is Performed

There are several types of oxygen-carrying proteins in the blood. One of them is methemoglobin. Normal methemoglobin levels in blood are usually 1%. If the level is higher, you can become sick because the protein is not carrying oxygen. This can make your blood look brown instead of red. Methemoglobinemia has several…

Normal Results

Normally, methylene blue quickly lowers the level of methemoglobin in the blood. Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results.

What Abnormal Results Mean

You may have a rare form of methemoglobinemia if this test does not significantly lower the blood level of methemoglobin.

Risks

There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Inserting an IV may be more difficult for you or your child than for other people. Other risks associated with this type of blood test are minor, but may…

References

Chernecky CC, Berger BJ. Methemoglobin - blood. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures . 6th ed. St Louis, MO: Elsevier Saunders; 2013:781-782. Neerja V, Graham S, Bem S. Basic examination of blood and bone marrow. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and…

This is a summary. Read the full article at www.ucsfbenioffchildrens.org (reviewed 13/10/2022).

This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.