LAB TEST

Myocardial biopsy

Myocardial biopsy is the removal of a small piece of heart muscle for examination.

How the Test is Performed

Myocardial biopsy is done through a catheter that is threaded into your heart ( cardiac catheterization ). The procedure will take place in a hospital radiology department, special procedures room, or cardiac diagnostics laboratory. To have the procedure: You may be given medicine to help you relax (sedative) before…

How to Prepare for the Test

You will be told not to eat or drink anything for 6 to 8 hours before the test. The procedure takes place in the hospital. Most often, you will be admitted the morning of the procedure, but in some cases, you may need to be admitted the night before. A health care provider will explain the procedure and its risks. You…

How the Test will Feel

You may feel some pressure at the biopsy site. You may have some discomfort due to lying still for a long period of time.

Why the Test is Performed

This procedure is routinely done after heart transplantation to watch for signs of rejection. Your provider may also order this procedure if you have signs of: Alcoholic cardiomyopathy Cardiac amyloidosis Cardiomyopathy Hypertrophic cardiomyopathy Idiopathic cardiomyopathy Ischemic cardiomyopathy Myocarditis…

Normal Results

A normal result means no abnormal heart muscle tissue was discovered. However, it does not necessarily mean your heart is normal because sometimes the biopsy can miss abnormal tissue.

What Abnormal Results Mean

An abnormal result means abnormal tissue was found. This test may reveal the cause of cardiomyopathy. Abnormal tissue may be due to: Amyloidosis Myocarditis Sarcoidosis Transplant (heart) rejection

Risks

Risks are moderate and include: Blood clots Bleeding from the biopsy site Cardiac arrhythmias Infection Injury to the recurrent laryngeal nerve Injury to the vein or artery Pneumothorax Rupture of the heart (very rare) Tricuspid regurgitation

References

Kliger CA, Sorajja P. Special techniques. In: Sorajja P, Lim MJ, Kern MJ, eds. Kern's Cardiac Catheterization Handbook . 7th ed. Philadelphia, PA: Elsevier; 2020:chap 9. Miller DV. Cardiovascular system. In: Goldblum JR, Lamps LW, McKenney JK, Myers JL, eds. Rosai and Ackerman's Surgical Pathology . 11th ed.…

This is a summary. Read the full article at www.ucsfbenioffchildrens.org (reviewed 08/05/2024).

This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.