LAB TEST
Quantitative Bence-Jones protein test
This test measures the level of abnormal proteins called Bence-Jones proteins in the urine.
How the Test is Performed
A clean-catch urine sample is needed. The clean-catch method is used to prevent germs from the penis or vagina from getting into a urine sample. To collect your urine, your health care provider may give you a special clean-catch kit that contains a cleansing solution and sterile wipes. Follow instructions exactly so…
How the Test will Feel
The test involves only normal urination, and there is no discomfort.
Why the Test is Performed
Bence-Jones proteins are a part of regular antibodies called light chains. These proteins are not normally in urine. Sometimes, when your body makes too many antibodies, the level of light chains also rises. Bence-Jones proteins are small enough to be filtered out by the kidneys. The proteins then spill into the…
Normal Results
A normal result means no Bence-Jones proteins are found in your urine.
What Abnormal Results Mean
Bence-Jones proteins are rarely found in urine. If they are, it is usually associated with multiple myeloma . An abnormal result may also be due to: An abnormal buildup of proteins in tissues and organs ( amyloidosis ) Blood cancer called chronic lymphocytic leukemia Lymph system cancer (lymphoma) Buildup in the blood…
Risks
There are no risks with this test.
References
Gertz MA, Dispenzieri A. Amyloidosis. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine . 27th ed. Philadelphia, PA: Elsevier; 2024:chap 174. Rajkumar SV, Dispenzieri A. Multiple myeloma and related disorders. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th…
This is a summary. Read the full article at www.ucsfbenioffchildrens.org (reviewed 17/06/2024).
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.