LAB TEST

TBG blood test

The TBG blood test measures the level of a protein that moves thyroid hormone throughout your body. This protein is called thyroxine-binding globulin (TBG).

How the Test is Performed

A blood sample is taken and then sent to a laboratory for testing.

How to Prepare for the Test

Certain drugs and medicines can affect test results. Your health care provider may tell you to stop taking a certain medicine for a short time before the test. Never stop taking any medicine without first talking to your provider. These medicines and drugs can increase TBG level: Estrogens, found in birth control…

How the Test will Feel

When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or slight bruising. This soon goes away.

Why the Test is Performed

This test may be done to diagnose problems with your thyroid.

Normal Results

Normal range is 13 to 39 micrograms per deciliter (mcg/dL), or 0.13 to 0.39 milligrams per liter (mg/L). Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different samples. Talk to your provider about the meaning of your specific test results.

What Abnormal Results Mean

An increased TBG level may be due to: Acute intermittent porphyria (a rare metabolic disorder) Hypothyroidism (underactive thyroid) Liver disease , such as hepatitis Pregnancy (TBG levels normally increased during pregnancy) Note: TBG levels are normally high in newborns. Decreased TBG levels may be due to: Acute…

Risks

There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others. Other risks of having blood drawn are slight, but may include: Excessive…

References

Faix JD. Thyroid function testing (thyrotropin, triiodothyronine, and thyroxine). In: Robertson RP, ed. DeGroot's Endocrinology . 8th ed. Philadelphia, PA: Elsevier; 2023:chap 68. Guber HA, Oprea M, Russell YX. Evaluation of endocrine function. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and…

This is a summary. Read the full article at www.ucsfbenioffchildrens.org (reviewed 28/02/2024).

This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.