LAB TEST
Thyroid peroxidase antibody
Thyroid peroxidase is a type of protein (called an enzyme ) that cells in the thyroid gland use to make thyroid hormone. If these enzymes leak out into the bloodstream (as when thyroid cells are damaged) the immune system makes antibodies against these proteins. The thyroid peroxidase antibody test measures these antibodies in the blood.
How the Test is Performed
A blood sample is needed.
How the Test will Feel
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.
Why the Test is Performed
This test is done to confirm the cause of thyroid problems, including Hashimoto thyroiditis . The test is also used to find out if an immune or autoimmune disorder is damaging the thyroid.
Normal Results
A negative test means the result is normal. Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different specimens. Talk to your health care provider about the meaning of your specific test results.
What Abnormal Results Mean
A positive test may be due to: Granulomatous or subacute thyroiditis (an immune reaction of the thyroid gland that often follows an upper respiratory infection) Hashimoto thyroiditis (a reaction of the immune system against the thyroid gland) High levels of these antibodies have also been linked with an increased risk…
Risks
There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others. Other risks associated with having blood drawn are slight, but may…
References
Brent GA, Weetman AP. Hypothyroidism and thyroiditis. In: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Textbook of Endocrinology . 14th ed. Philadelphia, PA: Elsevier; 2020:chap 13. Guber HA, Oprea M, Russell YX. Evaluation of endocrine function. In: McPherson RA, Pincus MR, eds. Henry's…
This is a summary. Read the full article at www.ucsfbenioffchildrens.org (reviewed 28/02/2024).
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.