Indications
Afrin is indicated for the treatment of nasal congestion associated with acute or chronic rhinitis, common cold, sinusitis, upper respiratory allergies, epistaxis and hay fever. It is also used as nasal decongestant in otitis media.
Pharmacology
Oxymetazoline Hydrochloride is an imidazoline derivative sympathomimetic amine. It is a direct agonist at α-adrenoceptors but has no action on β- adrenoceptors. It is used as a topical agent on the nasal mucosa, produces a rapid and long acting vasoconstriction of the arterioles, thus reducing the blood flow and diminishing swelling of the mucosa. This results in improved potency of the airway and better drainage of the nasal sinus.
Dosage and administration
Oxymetazoline nasal spray-
Adults and children (6 years of age and older) : 2 or 3 sprays in each nostril twice daily for 3-5 days.
Elderly : There is no need for dosage reduction in the elderly for nasal administration.
Children below 6 years of age : It is not suitable for children below 6 years of age.
Oxymetazoline nasal drop-
Adults & children 6 years of age : 2-3 drops of 0.05% Nasal Drops in each nostril twice daily in the morning and evening.
Children 2-5 years of age : 2-3 drops of 0.025% Nasal Drops in each nostril twice daily in the morning and evening
Interactions
Afrin loride Nasal preparation should not be given to patients being treated with MAO inhibitors or within 14 days of ceasing such treatment.
Contraindications
It is contraindicated in patients with cardiovascular disease, hyperthyroidism, prostatic enlargement, angle closure glaucoma and hypersensitivity to any of its ingredients.
Side effects
Occasionally it may cause local irritation and dryness of the mouth and throat. Temporarily discomfort such as burning, stinging, sneezing or increase in nasal discharge may occur.
Pregnancy and lactation
The safety of Oxymetazoline Hydrochloride Nasal Spray during pregnancy and lactation has not been established, but is not thought to constitute a hazard during those periods.
Precautions and warnings
Keep away from the eyes. The spray should not be used for longer than seven days without medical advice. Frequent or prolonged use may cause nasal congestion to recur or worsen.
Overdose
Overdose may give rise to local irritation and rebound congestion. Treatment need only be symptomatic.
Storage
Keep below 30° C temperature in a dry place, protect from light. Do not refrigerate or freeze. Keep out of the reach of children.
Similar brands of Oxymetazoline Hydrochloride (Nasal Preparation)
Common questions
What is Afrin used for?
Afrin is indicated for the treatment of nasal congestion associated with acute or chronic rhinitis, common cold, sinusitis, upper respiratory allergies, epistaxis and hay fever. It is also used as nasal decongestant in otitis media.
What is the generic name of Afrin?
Afrin contains Oxymetazoline Hydrochloride (Nasal Preparation), which belongs to the group: Nasal Anti-histamine preparations, Nasal Decongestants & Other Nasal Preparations.
Who makes Afrin?
Afrin is marketed in Bangladesh by Aristopharma Ltd..
How is Afrin taken?
Oxymetazoline nasal spray- Adults and children (6 years of age and older) : 2 or 3 sprays in each nostril twice daily for 3-5 days. Elderly : There is no need for dosage reduction in the elderly for nasal administration. Always follow your doctor's instructions.
What are the side effects of Afrin?
Occasionally it may cause local irritation and dryness of the mouth and throat. Temporarily discomfort such as burning, stinging, sneezing or increase in nasal discharge may occur.
Is Afrin safe in pregnancy?
The safety of Oxymetazoline Hydrochloride Nasal Spray during pregnancy and lactation has not been established, but is not thought to constitute a hazard during those periods. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.