Indications
Treatment of novel or re-emerging pandemic influenza virus infections (limited to cases in which other influenza antiviral drugs are ineffective or not sufficiently effective).
Pharmacology
Favipiravir is a new antiviral drug against influenza. It is metabolized into favipiravir ribosyl triphosphate (favipiravir RTP) by an intracellular enzyme, and favipiravir RTP selectively inhibits RNA polymerase (RNA-dependent RNA polymerase) of the influenza virus, preventing replication of the influenza virus. It is a drug with a mechanism of action different from that of the existing influenza antiviral drugs and effective against all types and sub-types of human influenza A, B, and C viruses in vitro, showing a wide range of anti-viral activity against various influenza virus strains including avian and swine viruses.
Dosage and administration
The usual adult dosage is 1600 mg of Favipiravir administered orally twice daily on Day 1, followed by 600 mg orally twice daily from Day 2 to Day 5 or as directed by physicians. The total treatment duration should be 5 days.
Interactions
In animal studies, decreased RBC production,and increases in liver function parameters such as AST, ALP, ALT and total bilirubin, and increased vacuolization in hepatocytes. Toxicity information regarding Akarvia in humans is not readily available.
Contraindications
Favipiravir is contraindicated for pregnant women and women who may possibly be pregnant.
Side effects
Most common side effects are Diarrhea and increase of blood uric acid levels.
Pregnancy and lactation
Favipiravir may cause delayed development or death of embryos during the early stage of pregnancy. Should not be given during pregnancy.
Precautions and warnings
Akarvia should not be given in pregnant women, requirement of the confirmation of non-pregnancy in women of childbearing potential before use, thorough contraception measures from the start of the treatment to 7 days after the end of the treatment. Caution should be taken for Hepatic and renal impaired patient or use Akarvia as per the direction of registered Physician
Overdose
In animal studies, decreased RBC production,and increases in liver function parameters such as AST, ALP, ALT and total bilirubin, and increased vacuolization in hepatocytes. Toxicity information regarding Akarvia in humans is not readily available.
Storage
Keep below 30°C temperature, protected from light & moisture. Keep out of the reach of children.
Similar brands of Favipiravir
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Favipira | Beacon Pharmaceuticals PLC | Tablet | 200 mg | ৳ 100.00per unit |
| 2 | Fluvigan | NIPRO JMI Pharma Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 3 | Verigan | Veritas Pharmaceuticals Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 4 | Favipir | Eskayef Pharmaceuticals Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 5 | Favinil | Square Pharmaceuticals PLC | Tablet | 200 mg | ৳ 200.00per unit |
| 6 | Biofavi | Biopharma Limited | Tablet | 200 mg | ৳ 200.00per unit |
| 7 | Fravir | Orion Pharma Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 8 | Favitab | The IBN SINA Pharmaceutical PLC | Tablet | 200 mg | ৳ 200.00per unit |
| 9 | Piravix | Radiant Pharmaceuticals Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 10 | Viraflu | Beximco Pharmaceuticals Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 11 | Piravir | ACME Laboratories Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 12 | Favilar | Popular Pharmaceuticals Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 13 | Favira | Drug International Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 14 | Faviravir | ACI Limited | Tablet | 200 mg | ৳ 200.00per unit |
| 15 | Unifav | UniMed UniHealth Pharmaceuticals Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 16 | Favivir | Opsonin Pharma Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 17 | Fapravir | Renata PLC | Tablet | 200 mg | ৳ 200.00per unit |
| 18 | Fapiravir | Healthcare Pharmaceuticals Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 19 | Rotagan | Concord Pharmaceuticals Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 20 | Toyavir | General Pharmaceuticals Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 21 | Ivrenas | Genvio Pharma Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 22 | Favirest | Everest Pharmaceuticals Ltd. | Tablet | 200 mg | ৳ 200.00per unit |
| 23 | Favigan | Ziska Pharmaceuticals Ltd. | Tablet | 200 mg | ৳ 400.00per unit |
Common questions
What is Akarvia used for?
Treatment of novel or re-emerging pandemic influenza virus infections (limited to cases in which other influenza antiviral drugs are ineffective or not sufficiently effective).
What is the generic name of Akarvia?
Akarvia contains Favipiravir, which belongs to the group: Anti-viral drugs.
Who makes Akarvia?
Akarvia is marketed in Bangladesh by Incepta Pharmaceuticals Ltd..
How much does Akarvia 200 mg cost?
The listed price is ৳ 200.00 per unit and ৳ 2.00 per strip. Prices can change, so check with your pharmacy.
How is Akarvia taken?
The usual adult dosage is 1600 mg of Favipiravir administered orally twice daily on Day 1, followed by 600 mg orally twice daily from Day 2 to Day 5 or as directed by physicians. The total treatment duration should be 5 days. Always follow your doctor's instructions.
What are the side effects of Akarvia?
Most common side effects are Diarrhea and increase of blood uric acid levels.
Is Akarvia safe in pregnancy?
Favipiravir may cause delayed development or death of embryos during the early stage of pregnancy. Should not be given during pregnancy. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.