Indications
Atofix ointment is used topically to treat atopic dermatitis, commonly known as eczema.
Pharmacology
Difamilast is a phosphodiesterase 4 (PDE4) inhibitor. It increases cyclic adenosine 3',5'-monophosphate (cAMP) concentration and consequently suppresses the production of inflammatory cytokines, exerting effects in treatment of atopic dermatitis.
Dosage and administration
The usual adult dosage is an appropriate amount of the Difamilast 1% ointment applied to the affected area twice daily. The usual pediatric dosage is an appropriate amount of the Difamilast 0.3% ointment applied to the affected area twice daily.
Contraindications
Difamilast is contraindicated in individuals with a known hypersensitivity to the drug.
Side effects
Well tolerated in recommended dosage. At higher dosage it may cause mild skin reactions at the site of application, such as redness, burning, or stinging.
Pregnancy and lactation
Difamilast is not recommended for pregnant women or women who may possibly be pregnant. For breastfeeding, safety profile has not been fully established.
Precautions and warnings
External use only. Atofix ointment is not for oral, ophthalmic, or intravaginal use.
If there is any hypersensitivity issue with the use of Atofix, treatment should be discontinued.
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Similar brands of Difamilast
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Atofix | Eskayef Pharmaceuticals Ltd. | Ointment | 0.3% w/w | Not listed |
Common questions
What is Atofix used for?
Atofix ointment is used topically to treat atopic dermatitis, commonly known as eczema.
What is the generic name of Atofix?
Atofix contains Difamilast.
Who makes Atofix?
Atofix is marketed in Bangladesh by Eskayef Pharmaceuticals Ltd..
How is Atofix taken?
The usual adult dosage is an appropriate amount of the Difamilast 1% ointment applied to the affected area twice daily. 3% ointment applied to the affected area twice daily. Always follow your doctor's instructions.
What are the side effects of Atofix?
Well tolerated in recommended dosage. At higher dosage it may cause mild skin reactions at the site of application, such as redness, burning, or stinging.
Is Atofix safe in pregnancy?
Difamilast is not recommended for pregnant women or women who may possibly be pregnant. For breastfeeding, safety profile has not been fully established. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.