Indications
Clindamycin and Tretinoin gel is indicated for the topical treatment of Acne vulgaris.
Pharmacology
This is a combination of lincosamide antibiotic Clindamycin phosphate and retinoid Tretinoin. Clindamycin binds with the 50s ribosomal subunit of susceptible bacteria and prevents elongation of peptide chain by interfering with the peptidyl transfer, thereby suppressing bacterial protein synthesis. Clindamycin inhibits the activity of Propionibacterium acne as reduces the occurrence of acne. Tretinoin decreases the cohesiveness of follicular epithelial cells and increases the turn over thereby brings the comedones out.
Dosage and administration
Before sleep : Wash the face gently with a mild soap and water, then pat the skin dry. Apply the Gel with finger tips through the face gently. In the morning : Apply a sunscreen after the application of Gel. Do not wash your face more than 2 or 3 times a day. Apply the sunscreen cream as needed. Safety and effectiveness in children below 12 years of age have not been established.
Interactions
Concomitant use of other potentially irritating topical products (medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, products with high concentrations of alcohol, astringents, spices or lime) should be approached with caution.
While using concomitantly with Erythromycin, the activity of both Clindamycin and Erythromycin are decreased. So, Clindamycin should not be used with Erythromycin concomitantly.
While using concomitantly with neuromuscular medicine, the activity of the neuromuscular medicine is increased. So, care should be taken during these concomitant uses.
Contraindications
Clindamycin and Tretinoin should not be administered to individuals who are hypersensitive to Clindamycin or Tretinoin or any other component of the Gel.
Side effects
Erythema, scaling, nasopharyngitis, dry skin, cough, sinusitis and diarrhea are the common side effects.
Pregnancy and lactation
It is not known whether Clindamycin or Tretinoin is excreted in human milk. Exercise special caution while applying Clindamycin or Tretinoin to a nursing mother.
Precautions and warnings
Clindamycin and Tretinoin should not be applied to eyes, nose, ear, lips, cut, burn and other infections. After the application of the Gel, keep away from sunlight.
Storage
Keep below 25°C temperature, away from light & moisture. Keep out of the reach of children.
Similar brands of Clindamycin + Tretinoin
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Clindacin Plus | Incepta Pharmaceuticals Ltd. | Topical Gel | 1.2%+0.025% | Not listed |
| 2 | Clindax Plus | Opsonin Pharma Ltd. | Topical Gel | 1.2%+0.025% | Not listed |
| 3 | Clinex Plus | Aristopharma Ltd. | Topical Gel | 1.2%+0.025% | Not listed |
| 4 | Clinface | Square Pharmaceuticals PLC | Topical Gel | 1.2%+0.025% | Not listed |
| 5 | Clinacyn T | Beximco Pharmaceuticals Ltd. | Topical Gel | 1.2%+0.025% | Not listed |
| 6 | Lindamax Plus | Eskayef Pharmaceuticals Ltd. | Topical Gel | 1.2%+0.025% | Not listed |
| 7 | Trunac | Pharmasia Limited | Topical Gel | 1.2%+0.025% | Not listed |
| 8 | Pimponil | Kumudini Pharma Ltd. | Topical Gel | 1.2%+0.025% | Not listed |
| 9 | Clintrix | The White Horse Pharmaceuticals Ltd. | Topical Gel | 1.2%+0.025% | Not listed |
| 10 | Dalatic Plus | Drug International Ltd. | Topical Gel | 1.2%+0.025% | Not listed |
| 11 | Daclin T | ACI Limited | Topical Gel | 1.2%+0.025% | Not listed |
| 12 | Clinda-A | Dermolive | Topical Gel | 1.2%+0.025% | Not listed |
Common questions
What is Cinamycin Plus used for?
Clindamycin and Tretinoin gel is indicated for the topical treatment of Acne vulgaris.
What is the generic name of Cinamycin Plus?
Cinamycin Plus contains Clindamycin + Tretinoin, which belongs to the group: Topical antibiotic & retinoid preparations.
Who makes Cinamycin Plus?
Cinamycin Plus is marketed in Bangladesh by The IBN SINA Pharmaceutical PLC.
How is Cinamycin Plus taken?
Before sleep : Wash the face gently with a mild soap and water, then pat the skin dry. Apply the Gel with finger tips through the face gently. Always follow your doctor's instructions.
What are the side effects of Cinamycin Plus?
Erythema, scaling, nasopharyngitis, dry skin, cough, sinusitis and diarrhea are the common side effects.
Is Cinamycin Plus safe in pregnancy?
It is not known whether Clindamycin or Tretinoin is excreted in human milk. Exercise special caution while applying Clindamycin or Tretinoin to a nursing mother. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.