Indications
Clovir is indicated for the treatment of Herpes simplex keratitis.
Pharmacology
Acyclovir is an antiviral agent which is highly active in vitro against Herpes simplex (HSV) types I and II and Varicella zoster viruses, but its toxicity to mammalian cells is low. Acyclovir is phosphorylated to the active compound Acyclovir triphosphate after entry into herpes infected cell. The first step in this process requires the presence of the viral-coded thymidine kinase. Acyclovir triphosphate acts as an inhibitor of and substrate for the herpes specified DNA polymerase preventing further viral DNA synthesis without affecting normal cellular processes.
Dosage and administration
The dosage for all age groups is the same. A 10 mm ribbon of the ointment should be placed inside the lower conjunctival sac five times a day at approximately four hourly intervals. Treatment should continue for at least 3 days after healing
Interactions
No clinically significant interactions have been identified.
Contraindications
Acyclovir is contraindicated in patients known to be hypersensitive to Acyclovir or Valacyclovir
Side effects
Very common: Superficial punctate keratopathy. This did not necessitate an early termination of therapy and healed without apparent sequelae. Common: Transient mild stinging of the eye occurring immediately following application, conjunctivitis. Rare: Blepharitis.
Pregnancy and lactation
Pregnancy category B. There are no adequate and well-controlled studies of Acyclovir in pregnant women. It is not known whether topically applied Acyclovir is excreted in breast milk.
Precautions and warnings
The recommended dosage, frequency of applications, and length of treatment should not be exceeded.
Overdose
No adverse effects would be expected if the entire contents of the tube containing 90 mg Clovir were ingested orally.
Storage
Store in a cool and dry place. Keep away from light. Keep out of reach of children. Do not touch the tip of the tube since this may contaminate the product. After one month of the opening do not use the medicine of tube.
Similar brands of Acyclovir (Ophthalmic)
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Optivir | Biopharma Limited | Ophthalmic Ointment | 3% | Not listed |
| 2 | Virupos | ZAS Corporation | Ophthalmic Ointment | 3% | Not listed |
| 3 | Cuvir | General Pharmaceuticals Ltd. | Ophthalmic Ointment | 3% | Not listed |
| 4 | Cyclovex | OSL Pharma Limited | Ophthalmic Ointment | 3% | Not listed |
| 5 | Virine | Nipa Pharmaceuticals Ltd. | Ophthalmic Ointment | 3% | Not listed |
Common questions
What is Clovir used for?
Clovir is indicated for the treatment of Herpes simplex keratitis.
What is the generic name of Clovir?
Clovir contains Acyclovir (Ophthalmic), which belongs to the group: Ophthalmic Anti-viral Products.
Who makes Clovir?
Clovir is marketed in Bangladesh by The IBN SINA Pharmaceutical PLC.
How is Clovir taken?
The dosage for all age groups is the same. A 10 mm ribbon of the ointment should be placed inside the lower conjunctival sac five times a day at approximately four hourly intervals. Always follow your doctor's instructions.
What are the side effects of Clovir?
Very common: Superficial punctate keratopathy. This did not necessitate an early termination of therapy and healed without apparent sequelae.
Is Clovir safe in pregnancy?
Pregnancy category B. There are no adequate and well-controlled studies of Acyclovir in pregnant women. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.