MEDICINE
Combo 4
0.05%+0.75%+2%+1% Cream · Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine
Indications
- Combo 4 cream is indicated in the treatment of-
- Mixed and complicated Fungal, Protozoal & Bacterial infections,
- Mild to moderate vaginitis,
- Candidiasis and trichomoniasis,
- Pruritus vulvae,
- Dermatitis,
- Eczema,
Genito-urinary infections.
Pharmacology
This cream is a combination cream which exhibits anti-bacterial, anti-fungal, anti-protozoal & anti-inflammatory actions. Ofloxacin is a broad-spectrum antibiotic that acts against many gram-positive & gram-negative bacteria. Ornidazole belongs to the nitroimidazole group of antibiotics and is used to treat amoeba and trichomonas infections. Terbinafine is an Allylamine antifungal that inhibits biosynthesis of Ergosterol (an essential components if fungal cell membrane) via inhibition of Squalene Epoxidase enzyme causing fungal cell death. Clobetasol is a potent corticosteroid which exhibits anti-inflammatory, anti-pruritic and vasoconstrictive properties.
Dosage and administration
Apply by gently rubbing onto the affected area twice daily.
Interactions
No hazardous interactions have been reported.
Contraindications
Contraindicated in patients hypersensitive to any of the components of the formulation.
Side effects
Burning, itching, irritation, dry skin
Pregnancy and lactation
The safe use of this preparation during pregnancy & lactation has not been established.
Precautions and warnings
Do not shallow. For external use only
Storage
Store below 30°C. keep away from light and out of the reach of children. Do not freeze.
Similar brands of Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Combicid | Square Pharmaceuticals PLC | Cream | 0.05%+0.75%+2%+1% | Not listed |
| 2 | Dermomix | Incepta Pharmaceuticals Ltd. | Cream | 0.05%+0.75%+2%+1% | Not listed |
| 3 | Dermacom | The IBN SINA Pharmaceutical PLC | Cream | 0.05%+0.75%+2%+1% | Not listed |
| 4 | Mycofree-OC | Drug International Ltd. | Cream | 0.05%+0.75%+2%+1% | Not listed |
| 5 | Axxo | General Pharmaceuticals Ltd. | Cream | 0.05%+0.75%+2%+1% | Not listed |
| 6 | Dermoquad | Healthcare Pharmaceuticals Ltd. | Cream | 0.05%+0.75%+2%+1% | Not listed |
| 7 | Tetramix | Popular Pharmaceuticals Ltd. | Cream | 0.05%+0.75%+2%+1% | Not listed |
| 8 | Combimax | Opsonin Pharma Ltd. | Cream | 0.05%+0.75%+2%+1% | Not listed |
Common questions
What is Combo 4 used for?
Combo 4 cream is indicated in the treatment of- Mixed and complicated Fungal, Protozoal & Bacterial infections, Mild to moderate vaginitis, Candidiasis and trichomoniasis, Pruritus vulvae, Dermatitis, Eczema, Genito-urinary infections.
What is the generic name of Combo 4?
Combo 4 contains Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine, which belongs to the group: 4-Quinolone preparations, Clobetasol / Clobetasone & Combined Preparations.
Who makes Combo 4?
Combo 4 is marketed in Bangladesh by ACME Laboratories Ltd..
How is Combo 4 taken?
Apply by gently rubbing onto the affected area twice daily. Always follow your doctor's instructions.
What are the side effects of Combo 4?
Burning, itching, irritation, dry skin
Is Combo 4 safe in pregnancy?
The safe use of this preparation during pregnancy & lactation has not been established. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.