Indications
Des is indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis, such as sneezing, nasal discharge & itching, congestion or stuffiness, as well as ocular itching, tearing and redness, itching of palate and coughing. Des is also indicated for the relief of symptoms associated with chronic idiopathic urticaria such as the relief of itching and the size & number of hives.
Pharmacology
Desloratadine, the major active metabolite of Loratadine, is a non-sedating; long acting tricyclic histamine antagonist with selective H1-receptor histamine antagonist activity. Desloratadine also inhibits histamine release from human mast cell.
Dosage and administration
Pediatric drops:
Child 6-11 months of age : 2 ml drops once daily.
Child 1-2 years of age : 2.5 ml drops once daily.
Syrup:
Child 6-11 months of age : 2 ml once daily.
Child 1-5 years of age : 2.5 ml once daily.
Child 6-11 years of age : 5 ml once daily.
Adults & >12 years of age : 10 ml once daily.
Tablet:
Adults and children 12 years of age and over : 1 tablet daily
Interactions
No clinically relevant drug interactions have been reported.
Contraindications
Desloratadine is contraindicated in patients having hypersensitivity to this medication or to any of its ingredients or Loratadine.
Side effects
Less common side effects may include headache, nausea, fatigue, dizziness, pharyngitis, dyspepsia and myalgia.
Pregnancy and lactation
Pregnancy Category C. The safe use of Desloratadine during pregnancy has not been established. Therefore, Desloratadine is not to be used during pregnancy unless clearly indicated. Desloratadine passes into breast milk, therefore a decision should be made whether to discontinue nursing or to discontinue Desloratadine taking into account the importance of the drug to the mother.
Precautions and warnings
In adult patients with liver or renal impairment: A starting dose of one 5 mg tablet every other day is recommended based on pharmacokinetic data. If the patient has medical or familial history of seizures.
Overdose
No clinically relevant adverse effects have been reported.
Storage
Store in a cool & dry place, protected from light. Store below 30°C. Keep all medicines out of the reach of children.
Similar brands of Desloratadine
Common questions
What is Des used for?
Des is indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis, such as sneezing, nasal discharge & itching, congestion or stuffiness, as well as ocular itching, tearing and redness, itching of palate and coughing. Des is also indicated for the relief of symptoms associated with chronic idiopathic urticaria such as the…
What is the generic name of Des?
Des contains Desloratadine, which belongs to the group: Anti-histamine.
Who makes Des?
Des is marketed in Bangladesh by Opsonin Pharma Ltd..
How is Des taken?
Pediatric drops: Child 6-11 months of age : 2 ml drops once daily. 5 ml drops once daily. Always follow your doctor's instructions.
What are the side effects of Des?
Less common side effects may include headache, nausea, fatigue, dizziness, pharyngitis, dyspepsia and myalgia.
Is Des safe in pregnancy?
Pregnancy Category C. The safe use of Desloratadine during pregnancy has not been established. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.