Indications
This syrup is indicated for the relief of cough, associated congestive symptoms and aiding restful sleep.
Pharmacology
Guaifenesin is reported to reduce the viscosity of tenacious sputum end is used as an expectorant. Levomenthol has mild local anesthetic and decongestant properties. Diphenhydramine Hydrochloride possesses antitussive, antihistaminic, and anticholinergic properties.
Dosage and administration
For adults and children over 12 years : 2 teaspoonfuls syrup 4 times a day or as directed by the physicians. Do not take more than 8 teaspoonful syrup in 24 hours. Use in Children & Adolescents : The efficacy and safety of Guaifenesin have not been established in pediatric patients and adolescents.
Interactions
This syrup contains Diphenhydramine Hydrochloride and therefore may potentiate the effects of alcohol, and other CNS depressants. As Diphenhydramine Hydrochloride possess some anticholinergic activity, the effects of anticholinergics (e.g. some psychotrophic drugs and atropine) may be potentiated by E-Cof Plus. This may result in tachycardia, mouth dryness, gastrointestinal disturbances (e.g. colic), urinary retention and headache.
Contraindications
This syrup is contraindicated in individuals with known hypersensitivity to the product or any of its components. This medicine should not be administered to patients who have received treatment with MAOIs within last two weeks.
Side effects
This syrup may cause drowsiness, dizziness, nausea and vomiting, gastro-intestinal disturbance, dry mouth, nose and throat difficulty in urination or blurred vision.
Pregnancy and lactation
As with any other medicine, care should be taken In administration during pregnancy. This product has not been associated with adverse effects in the human fetus or suckling infant.
Precautions and warnings
This syrup may cause drowsiness; if affected, individuals should not drive or operate machinery. Diphenhydramine Hydrochloride should not be taken by individuals with narrow-angle glaucoma or symptomatic prostatic hypertrophy. E-Cof Plus should not be used for persistent or chronic cough, such as occurs with asthma, or where cough is accompanied by excessive secretions unless directed by a physician.
Overdose
When taken in excess, Guaifenesin may cause renal calculi. Treatment of overdose should be symptomatic and supportive.
Storage
Store at a temperature not exceeding 30° C in a dry place. Protect from light & moisture. Keep out of the reach of children.
Similar brands of Guaifenesin + Levomenthol + Diphenhydramine
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Tusca Plus | Square Pharmaceuticals PLC | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 2 | Tuscof | Eskayef Pharmaceuticals Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 3 | Pires-M | Navana Pharmaceuticals Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 4 | Daykof | Beacon Pharmaceuticals PLC | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 5 | Ezykof Plus | Popular Pharmaceuticals Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 6 | Extopel | General Pharmaceuticals Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 7 | Nixcof | Opsonin Pharma Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 8 | Sintos | ACME Laboratories Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 9 | Respi-M | Silva Pharmaceuticals Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 10 | Extil Plus | Albion Laboratories Limited | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 11 | Kof-free | Benham Pharmaceuticals Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 12 | Cofson plus | Hudson Pharmaceuticals Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 13 | Klinkof-M | Novatek Pharmaceuticals Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 14 | Tesco GL | Techno Drugs Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 15 | Antikof | Ad-din Pharmaceuticals Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 16 | Sinoline | Incepta Pharmaceuticals Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 17 | Clecof | One Pharma Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
| 18 | Antuss Plus | Gaco Pharmaceuticals Ltd. | Syrup | (100 mg+1.1 mg+14 mg)/5 ml | Not listed |
Common questions
What is E-Cof Plus used for?
This syrup is indicated for the relief of cough, associated congestive symptoms and aiding restful sleep.
What is the generic name of E-Cof Plus?
E-Cof Plus contains Guaifenesin + Levomenthol + Diphenhydramine, which belongs to the group: Combined cough expectorants.
Who makes E-Cof Plus?
E-Cof Plus is marketed in Bangladesh by Edruc Limited.
How is E-Cof Plus taken?
For adults and children over 12 years : 2 teaspoonfuls syrup 4 times a day or as directed by the physicians. Do not take more than 8 teaspoonful syrup in 24 hours. Always follow your doctor's instructions.
What are the side effects of E-Cof Plus?
This syrup may cause drowsiness, dizziness, nausea and vomiting, gastro-intestinal disturbance, dry mouth, nose and throat difficulty in urination or blurred vision.
Is E-Cof Plus safe in pregnancy?
As with any other medicine, care should be taken In administration during pregnancy. This product has not been associated with adverse effects in the human fetus or suckling infant. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.