Indications
Gaba is indicated for-
Neuropathic Pain.
Adjunctive therapy in partial seizure and secondary generalized seizure.
Pharmacology
Gabapentin is an anti-convulsant. It is a structural analog of gamma-amino-butyric-acid (GABA). All pharmacological actions following administration of Gabapentin are due to the activity of parent compound. Gabapentin binds with the alpha-2-delta subunit of voltage gated L-type Calcium channel, and inhibits branched chain amino acid transferase & probably inhibits neurotransmitter release of excitatory amino acid.
Dosage and administration
Neuropathic Pain : The treatment may be initiated as a single 300 mg dose on Day-1, than 300 mg twice on Day-2 and 300 mg thrice on Day-3. The dose can be subsequently be titrated up as needed for pain relief to a daily dose of 1800 mg (divided TID). Epilepsy:
Patients over 12 years of age: the effective dose of Gabapentin is 900 to 1800 mg/day given in three divided doses. The starting dose is 300 mg three times a day.
Paediatric patients age 3-12 year: the starting dose should range from 10-15 mg/kg/day in 3 divided doses, and the effective dose reached by upward titration over a period of approximately three days.
Interactions
Antacids may reduce the bioavailability of Gaba by up to 20 %. Cimetidine may alter its reanal excretion. Gaba does not interact with other anti-epileptic drug or with oral contraceptive preparations.
Contraindications
Gabapentin is contraindicated in patients who have known hypersensitivity to the drug.
Side effects
Fatigue, Dizziness, ataxia, weight gain, peripheral edema, dry mouth and somnolence may occur.
Pregnancy and lactation
Pregnancy category C. it should be used during pregnancy only if potential benefits justifies the potential risk to the fetus. Gabapentin may be secreted through the breast milk. So it should be used during lactation only if potential benefits justifies the potential risk to the baby.
Precautions and warnings
Patients should be instructed to take Gaba only as prescribed. While using Gaba patients should be instructed either not to drive a car or to operate other complex machinery until they have gained sufficient experiences about Gaba whether or not it affects their mental and/or motor performance adversely.
Storage
Store below 25°C temperature. Protect from light and moisture. Keep all the medicines out of the reach of the children.
Similar brands of Gabapentin
Common questions
What is Gaba used for?
Gaba is indicated for- Neuropathic Pain. Adjunctive therapy in partial seizure and secondary generalized seizure.
What is the generic name of Gaba?
Gaba contains Gabapentin, which belongs to the group: Adjunct anti-epileptic drugs.
Who makes Gaba?
Gaba is marketed in Bangladesh by Renata PLC.
How much does Gaba 300 mg cost?
The listed price is ৳ 16.07 per unit and ৳ 160.70 per strip. Prices can change, so check with your pharmacy.
How is Gaba taken?
Neuropathic Pain : The treatment may be initiated as a single 300 mg dose on Day-1, than 300 mg twice on Day-2 and 300 mg thrice on Day-3. The dose can be subsequently be titrated up as needed for pain relief to a daily dose of 1800 mg (divided TID). Always follow your doctor's instructions.
What are the side effects of Gaba?
Fatigue, Dizziness, ataxia, weight gain, peripheral edema, dry mouth and somnolence may occur.
Is Gaba safe in pregnancy?
Pregnancy category C. it should be used during pregnancy only if potential benefits justifies the potential risk to the fetus. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.