Indications
Gatsina eye drops is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms: Aerobic Gram-Positive Bacteria:
- Corynebacterium propinquum
- Staphylococcus aureus
- Staphylococcus epidermidis
- Streptococcus mitis
- Streptococcus pneumoniae
- Aerobic Gram-Negative Bacteria:
Haemophilus influenzae.
Pharmacology
Gatifloxacin eye drops is an 8-methoxyfluoroquinolone anti-infective for topical ophthalmic use. The antibacterial action of Gatifloxacin results from inhibition of DNA gyrase and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division. It appears that the C-8-methoxy moiety contributes to enhanced activity and lower selection of resistant mutants of gram-positive bacteria compared to the nonmethoxy C-8 moiety.
Dosage and administration
Gatifloxacin 0.3% : The recommended dosage regimen for the treatment of bacterial conjunctivitis is:
Days 1 and 2: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times daily.
Days 3 through 7: Instill one drop up to 4 times daily while awake.
Gatifloxacin 0.5% : Patients 1 year of age or older:
Day 1: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times.
Days 2 through 7: Instill one drop two to four times daily in the affected eye(s) while awake.
Interactions
Specific drug interaction studies have not been conducted with Gatsina eye drops.
Contraindications
Gatifloxacin eye drops is contraindicated in patients with a history of hypersensitivity to Gatifloxacin, to other quinolones, or to any of the components in this medication. Gatifloxacin eye drops should not be injected subconjunctivally, nor should it be introduced directly into the anterior chamber of the eye.
Side effects
The most frequently reported adverse events in the overall study population were conjunctival irritation, increased lacrimation etc.
Pregnancy and lactation
Because there are no adequate and well-controlled studies in pregnant women, Gatifloxacin eye drops should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Gatifloxacin is administered to a nursing woman.
Precautions and warnings
Patients should be advised not to wear contact lenses if they have signs and symptoms of bacterial conjunctivitis. Avoid contaminating the applicator tip with material from the eye, fingers or other source.
Overdose
An overdose of this medication is unlikely to threaten life.
Storage
Protect from light. Store in cool & dry place; keep out of the reach of children. Do not use more than 4 weeks after opening.
Similar brands of Gatifloxacin
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Zymar | Eskayef Pharmaceuticals Ltd. | Ophthalmic Solution | 0.3% | Not listed |
| 2 | Gatiflox | Incepta Pharmaceuticals Ltd. | Ophthalmic Solution | 0.3% | Not listed |
| 3 | Gatigen | General Pharmaceuticals Ltd. | Ophthalmic Solution | 0.3% | Not listed |
| 4 | Tget | Opsonin Pharma Ltd. | Ophthalmic Solution | 0.3% | Not listed |
| 5 | Gatipro | OSL Pharma Limited | Ophthalmic Solution | 0.3% | Not listed |
| 6 | Gatibac | Popular Pharmaceuticals Ltd. | Ophthalmic Solution | 0.3% | Not listed |
| 7 | Tag | Aristopharma Ltd. | Ophthalmic Solution | 0.3% | Not listed |
| 8 | Gatiflox ES | Incepta Pharmaceuticals Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 9 | Gatipro | OSL Pharma Limited | Ophthalmic Solution | 0.5% | Not listed |
| 10 | Zymarin | Eskayef Pharmaceuticals Ltd. | Ophthalmic Solution | 0.5% | Not listed |
Common questions
What is Gatsina used for?
Gatsina eye drops is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms: Aerobic Gram-Positive Bacteria: Corynebacterium propinquum Staphylococcus aureus Staphylococcus epidermidis Streptococcus mitis Streptococcus pneumoniae Aerobic Gram-Negative Bacteria: Haemophilus influenzae.
What is the generic name of Gatsina?
Gatsina contains Gatifloxacin, which belongs to the group: Ophthalmic antibacterial drugs.
Who makes Gatsina?
Gatsina is marketed in Bangladesh by The IBN SINA Pharmaceutical PLC.
How is Gatsina taken?
3% : The recommended dosage regimen for the treatment of bacterial conjunctivitis is: Days 1 and 2: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times daily. Days 3 through 7: Instill one drop up to 4 times daily while awake. Always follow your doctor's instructions.
What are the side effects of Gatsina?
The most frequently reported adverse events in the overall study population were conjunctival irritation, increased lacrimation etc.
Is Gatsina safe in pregnancy?
Because there are no adequate and well-controlled studies in pregnant women, Gatifloxacin eye drops should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this drug is excreted in human milk. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.