Indications
Topical antiseptic as first aid to help prevent infection in minor cuts, scrapes and burns.
Pharmacology
In aqueous solutions Gentian violet (GV) dissociates into positive (GV+)and negative ions (Cl-) that penetrate through the wall and membrane of both gram-positive and gram-negative bacterial cells. The GV+ interacts with negatively charged components of bacterial cells including the lipopolysaccharide (on the cell wall), the peptidoglycan and DNA. A similar cell penetration and DNA binding process is thought to take place for fungal cells as well. Because Gentian violet is a mutagen and mitotic poison, cell growth is consequently inhibited. A photodynamic action of gentian violet, apparently mediated by a free-radical mechanism, has recently been described in bacteria and in the protozoan T. cruzi. Evidence also suggests that gentian violet dissipates the bacterial (and mitochondrial) membrane potential by inducing permeability. This is followed by respiratory inhibition. This anti-mitochondrial activity might explain gentian violet's efficacy towards both bacteria and yeast with relatively mild effects on mammalian cells.
Dosage and administration
Clean the affected area and apply a small amount of this product on the area 1 to 3 times daily. May be covered with a sterile bandage.
Interactions
There are no known drug interactions and none well documented.
Contraindications
Do not apply to an ulcerative lesion as this may cause tattoing of the skin.
Side effects
Redness, irritation, swelling or pain persists or increases of if infection occurs.
Pregnancy and lactation
Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category.
Precautions and warnings
Stop use if the condition persists or gets worse. Do not use longer than 1 week.
Similar brands of Gentian Violet
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Gentian Violet | Momotaz Pharmaceuticals Ltd. | Topical Solution | 2% | Not listed |
| 2 | Viola | Kawsar Chemicals | Topical Solution | 2% | Not listed |
| 3 | Viola | Kawsar Chemicals | Topical Solution | 1% | Not listed |
Common questions
What is Gention Violet used for?
Topical antiseptic as first aid to help prevent infection in minor cuts, scrapes and burns.
What is the generic name of Gention Violet?
Gention Violet contains Gentian Violet, which belongs to the group: Crystal violet/ Gentian violet preparations.
Who makes Gention Violet?
Gention Violet is marketed in Bangladesh by Pharmik Laboratories Ltd..
How is Gention Violet taken?
Clean the affected area and apply a small amount of this product on the area 1 to 3 times daily. May be covered with a sterile bandage. Always follow your doctor's instructions.
What are the side effects of Gention Violet?
Redness, irritation, swelling or pain persists or increases of if infection occurs.
Is Gention Violet safe in pregnancy?
Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.