Indications
- Histasip is indicated in the following indications-
- Urticaria
- Sensitivity reactions
- Angioneurotic edema
- Vasomotor rhinitis
- Cough
- Common cold
- Motion sickness and
Other allergic conditions.
Pharmacology
Chlorpheniramine Maleate is an alkylamine antihistamine. It is one of the most potent histamine H1-receptor blocking agents which is used as a potent antihistamine. This generally causes less sedation than promethazine. Chlorpheniramine Maleate exerts its effects by blocking H1-receptor competitively.
Dosage and administration
Adult- Usual adult dose is 4 mg every 4-6 hours, maximum 24 mg daily. Child-
6-12 years: 2 mg every 4-6 hours, maximum 12 mg daily.
2-5 years: 1 mg every 4-6 hours, maximum 6 mg daily.
1-2 years: 1 mg twice daily.
Below 1 year the use of Chlorpheniramine Maleate is not recommended.
Interactions
Chlorphenamine maleate has been reported to be incompatible with calcium chloride, kanamycin sulfate, noradrenaline acid tartrate, pentobarbital sodium, and meglumine adipiodone.
Contraindications
Chlorpheniramine is contraindicated in patients hypersensitive to this agent, in newborn or premature infants.
Side effects
Histasip is well-tolerated, but sometimes drowsiness, dizziness, muscular weakness, and gastrointestinal upset may occur.
Pregnancy and lactation
This drug should not be used in lactating mother and in pregnancy especially during the first trimester of pregnancy.
Precautions and warnings
Histasip should be used with caution in patients with glaucoma and prostatic hypertrophy. During therapy with chlorpheniramine, caution should be taken in driving vehicles and operating machinery.
Overdose
CNS depression (including sedation, apnea, CV collapse), CNS stimulation (including insomnia, hallucination, tremors, convulsions), tinnitus, blurred vision, dizziness, ataxia, hypotension. Stimulation and atropine-like signs and symptoms (including dry mouth, fixed dilated pupils, flushing, hyperthermia, Gl symptoms) are more likely in children.
Storage
Store in a cool (Below 25°C temperature) and dry place protected from light. Keep out of the reach of children.
Similar brands of Chlorpheniramine Maleate
Common questions
What is Histasip used for?
Histasip is indicated in the following indications- Urticaria Sensitivity reactions Angioneurotic edema Vasomotor rhinitis Cough Common cold Motion sickness and Other allergic conditions.
What is the generic name of Histasip?
Histasip contains Chlorpheniramine Maleate, which belongs to the group: Anti-histamine.
Who makes Histasip?
Histasip is marketed in Bangladesh by Aztec Pharmaceuticals Ltd..
How is Histasip taken?
Adult- Usual adult dose is 4 mg every 4-6 hours, maximum 24 mg daily. Child- 6-12 years: 2 mg every 4-6 hours, maximum 12 mg daily. Always follow your doctor's instructions.
What are the side effects of Histasip?
Histasip is well-tolerated, but sometimes drowsiness, dizziness, muscular weakness, and gastrointestinal upset may occur.
Is Histasip safe in pregnancy?
This drug should not be used in lactating mother and in pregnancy especially during the first trimester of pregnancy. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.