Indications
Homatropine eye drops is indicated for use as a mydriatic and cycloplegic.
Pharmacology
Homatropine is a competitive muscarinic receptor antagonist with a bulky aromatic group in place of the acetyl group of acetylcholine. It is expected to act in similar manner as atropine, producing similar parasympatholytic effects. By blocking muscarinic receptors and cholinergic signalling pathways, homatropine blocks the response of the iris sphincter muscle and cause the pupil to become unresponsive to light upon dilation or mydriasis. It also blocks the accommodative muscle of the ciliary body to cholinergic stimulation.
Dosage and administration
For refraction : Instill two drops in the eye(s) and repeat 2-3 times at 5-10 minute intervals. For therapy : Instill 1-2 drops in the eye(s) every 3-4 hours. Use in children : Should not be used in children below the age of 3 months.
Interactions
Effects may be increased by drugs with antimuscarinic effect such as; some antihistamines; phenothiazines; antipsychotics; TCAs; MAOIs or parasympathomimetics.
Contraindications
Contraindicated in patients with closed-angle glaucoma or with a narrow angle between the iris and the cornea.
Side effects
Hypersensitivity may occur as conjunctivitis.
Pregnancy and lactation
There are no adequate and well-controlled studies in pregnant women. Matropin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Homatropine is excreted in human milk. Caution should be exercised when Matropin is administered to a nursing mother.
Precautions and warnings
Should be used with caution in patients with prostatic enlargement and in patients suffering from paralytic ileus or pyloric stenosis.
Storage
Store in a cool & dry place, protect from light. Do not use longer than 30 days after first opening. Keep out of the reach of children.
Similar brands of Homatropine Hydrobromide
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Hemomin | Nipa Pharmaceuticals Ltd. | Ophthalmic Solution | 2% | Not listed |
| 2 | Matropin | Aristopharma Ltd. | Ophthalmic Solution | 2% | Not listed |
Common questions
What is Homatropine used for?
Homatropine eye drops is indicated for use as a mydriatic and cycloplegic.
What is the generic name of Homatropine?
Homatropine contains Homatropine Hydrobromide, which belongs to the group: Mydriatic and Cycloplegic agents.
Who makes Homatropine?
Homatropine is marketed in Bangladesh by Reman Drug Laboratories Ltd..
How is Homatropine taken?
For refraction : Instill two drops in the eye(s) and repeat 2-3 times at 5-10 minute intervals. For therapy : Instill 1-2 drops in the eye(s) every 3-4 hours. Always follow your doctor's instructions.
What are the side effects of Homatropine?
Hypersensitivity may occur as conjunctivitis.
Is Homatropine safe in pregnancy?
There are no adequate and well-controlled studies in pregnant women. Matropin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.