Indications
Leobutol is indicated for the treatment or prevention of bronchospasm in adults, adolescents and children 6 years of age and older with reversible obstructive airway disease.
Pharmacology
Levosalbutamol is a single isomer beta 2-agonist that differs from racemic salbutamol by elimination of (S)-salbutamol. Levosalbutamol is an effective bronchodilator whose primary mechanism of action is unimpeded by (S)-salbutamol. Thus, when compared with racemic salbutamol, clinically comparable bronchodilation can be achieved with doses that substantially lessen beta-mediated side effects.
Dosage and administration
Tablet-
Adults and adolescents above 12 years: 1-2 mg three times daily.
Children (6 -11 years): 1 mg three times daily.
Syrup-
Adults : 5-10 ml three times daily.
Childrn (6-11 years): 5 ml three times daily.
Interactions
Other short acting sympathomimetic bronchodilators or epinephrine should be used with caution with Leobutol. If additional adrenergic drugs are to be administered by any route, they will be used with caution to avoid deleterious cardiovascular effects.
Contraindications
Levosalbutamol is contraindicated in patients with a history of hypersensitivity to levosalbutamol or any of its components.
Side effects
Hypocalcaemia, palpitation, fine tremors of the skeletal muscle and muscle cramps may occur. The other likely side effects are nausea, vomiting, burning substernal or epigastric pain and diarrhoea.
Pregnancy and lactation
The drug should be used during pregnancy only if the potential benefit justifies the potential risk of the fetus. It is not known whether Levosalbutamol is excreted in human milk. Caution should be exercised when oral Levosalbutamol is administered to a nursing woman.
Precautions and warnings
Particular caution is advised in acute severe asthma as this effect may be potentiated by hypoxia and by concomitant treatment with xanthine derivatives, steroids and diuretics. Serum potassium levels should be monitored in such situations.
Overdose
The expected symptoms with over dosage are those of excessive beta-adrenergic stimulation and the symptoms listed under side effects. In the event of serious poisoning, the stomach should be emptied and, if necessary, a beta-blocker administered with caution in patients with a history of bronchospasm.
Storage
Keep all medicines out of reach of children. Store in a cool and dry place, protected from light.
Similar brands of Levosalbutamol (Oral)
Common questions
What is Leobutol used for?
Leobutol is indicated for the treatment or prevention of bronchospasm in adults, adolescents and children 6 years of age and older with reversible obstructive airway disease.
What is the generic name of Leobutol?
Leobutol contains Levosalbutamol (Oral), which belongs to the group: Short-acting selective & β2-adrenoceptor stimulants.
Who makes Leobutol?
Leobutol is marketed in Bangladesh by Union Pharmaceuticals Ltd.
How is Leobutol taken?
Tablet- Adults and adolescents above 12 years: 1-2 mg three times daily. Children (6 -11 years): 1 mg three times daily. Always follow your doctor's instructions.
What are the side effects of Leobutol?
Hypocalcaemia, palpitation, fine tremors of the skeletal muscle and muscle cramps may occur. The other likely side effects are nausea, vomiting, burning substernal or epigastric pain and diarrhoea.
Is Leobutol safe in pregnancy?
The drug should be used during pregnancy only if the potential benefit justifies the potential risk of the fetus. It is not known whether Levosalbutamol is excreted in human milk. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.