Indications
Macflox tablet is indicated for the treatment of acute bacterial sinusitis, acute exacerbation of chronic bronchitis, community acquired pneumonia, uncomplicated & complicated skin and skin structure infections, complicated intra-abdominal infections and pelvic inflammatory disease.
Pharmacology
Moxifloxacin is a 4th generation synthetic broad spectrum, fluoroquinolone class of antibacterial drug. It has activity against a wide range of gram-positive, gram-negative, anaerobic and atypical bacteria including Mycoplasma pneumoniae. It acts by inhibiting topoisomerase II (DNA gyrase) and topoisomerase IV which are necessary for bacterial DNA replication, transcription & repair.
Dosage and administration
Acute bacterial sinusitis : 400 mg once daily 7-10 days. Acute bacterial exacerbation of chronic bronchitis : 400 mg once daily 5-10 days. Community-acquired pneumonia : 400 mg once daily 7-14 days. Uncomplicated skin and skin structure infections : 400 mg once daily 7 days. Complicated skin and skin structure infections : 400 mg once daily 7-21 days. Complicated intra-abdominal infections : 400 mg once daily 5-14 days. Pelvic inflammatory disease : 400 mg once daily 14 days.
Interactions
Macflox absorption is decreased when administered with antacids, sucralfate, multivitamins, and multivalent cations (e.g. iron or zinc). Macflox may enhance the risk of convulsions with NSAIDs and bleeding with warfarin. So concomitant use of Macflox with them should be avoided.
Contraindications
It is contraindicated in patients with a history of hypersensitivity to Moxifloxacin or other quinolones.
Side effects
Common side effects of Macflox include nausea, vomiting, diarrhea, headache and dizziness.
Pregnancy and lactation
US FDA pregnancy category C. Moxifloxacin is not recommended during pregnancy & lactation.
Precautions and warnings
Macflox may cause an increased risk of tendinitis and tendon rupture. It should be discontinued if pain or inflammation in a tendon occurs. It should not be used in patients with known prolongation of the QT interval, patients with uncorrected hypokalemia, and patients with receiving Class IA or Class III antiarrhythmic agents
Storage
Keep in a dry place, away from light and heat. Keep out of the reach of children.
Similar brands of Moxifloxacin Hydrochloride (Tablet)
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Moxihil | Goodman Pharmaceuticals Ltd. | Tablet | 400 mg | ৳ 35.00per unit |
| 2 | Moxidal | Biogen Pharmaceuticals Ltd. | Tablet | 400 mg | ৳ 35.00per unit |
| 3 | Maxiflox | ACI Limited | Tablet | 400 mg | ৳ 35.00per unit |
| 4 | Odycin | Beximco Pharmaceuticals Ltd. | Tablet | 400 mg | ৳ 40.00per unit |
| 5 | Moxif | Biopharma Limited | Tablet | 400 mg | ৳ 40.00per unit |
| 6 | Floromox | The IBN SINA Pharmaceutical PLC | Tablet | 400 mg | ৳ 40.00per unit |
| 7 | Moxigen | General Pharmaceuticals Ltd. | Tablet | 400 mg | ৳ 40.00per unit |
| 8 | Zydus | Healthcare Pharmaceuticals Ltd. | Tablet | 400 mg | ৳ 40.00per unit |
| 9 | Maximox | Orion Pharma Ltd. | Tablet | 400 mg | ৳ 40.00per unit |
| 10 | Xiomox | Renata PLC | Tablet | 400 mg | ৳ 40.00per unit |
| 11 | Respamox | Somatec Pharmaceuticals Ltd. | Tablet | 400 mg | ৳ 40.00per unit |
| 12 | Topomox | Leon Pharmaceuticals Ltd. | Tablet | 400 mg | ৳ 40.00per unit |
| 13 | Revalon | NIPRO JMI Pharma Ltd. | Tablet | 400 mg | ৳ 40.00per unit |
| 14 | Moxquin | Incepta Pharmaceuticals Ltd. | Tablet | 400 mg | ৳ 40.00per unit |
| 15 | Moxier | Euro Pharma Ltd. | Tablet | 400 mg | ৳ 40.00per unit |
| 16 | Moxana | Synovia Pharma PLC. | Tablet | 400 mg | ৳ 45.00per unit |
| 17 | Floxalone | Drug International Ltd. | Tablet | 400 mg | ৳ 45.00per unit |
| 18 | Moxilocin | Opsonin Pharma Ltd. | Tablet | 400 mg | ৳ 45.00per unit |
| 19 | Visomox | Eskayef Pharmaceuticals Ltd. | Tablet | 400 mg | ৳ 45.00per unit |
| 20 | Moxibest | One Pharma Ltd. | Tablet | 400 mg | ৳ 45.00per unit |
| 21 | MQ-4 | Silco Pharmaceutical Ltd. | Tablet | 400 mg | ৳ 47.00per unit |
| 22 | Moxiwin | Salton Pharmaceuticals Ltd. | Tablet | 400 mg | ৳ 50.00per unit |
| 23 | Iventi | Square Pharmaceuticals PLC | Tablet | 400 mg | ৳ 50.00per unit |
| 24 | Moxkil | Naafco Pharma PLC | Tablet | 400 mg | ৳ 50.00per unit |
| 25 | Flomox | OSL Pharma Limited | Tablet | 400 mg | ৳ 50.00per unit |
| 26 | Moxiwell | National Drug Co. Ltd. | Tablet | 400 mg | ৳ 50.00per unit |
| 27 | Moxiflox | Alco Pharma Ltd. | Tablet | 400 mg | ৳ 50.15per unit |
| 28 | Eramox | Beacon Pharmaceuticals PLC | Tablet | 400 mg | ৳ 60.00per unit |
| 29 | Verimox | Veritas Pharmaceuticals Ltd. | Tablet | 400 mg | ৳ 60.00per unit |
| 30 | Avaflox | UniMed UniHealth Pharmaceuticals Ltd. | Tablet | 400 mg | ৳ 70.00per unit |
Common questions
What is Macflox used for?
Macflox tablet is indicated for the treatment of acute bacterial sinusitis, acute exacerbation of chronic bronchitis, community acquired pneumonia, uncomplicated & complicated skin and skin structure infections, complicated intra-abdominal infections and pelvic inflammatory disease.
What is the generic name of Macflox?
Macflox contains Moxifloxacin Hydrochloride (Tablet), which belongs to the group: 4-Quinolone preparations.
Who makes Macflox?
Macflox is marketed in Bangladesh by Nuvista Pharma Ltd..
How much does Macflox 400 mg cost?
The listed price is ৳ 50.00 per unit and ৳ 500.00 per strip. Prices can change, so check with your pharmacy.
How is Macflox taken?
Acute bacterial sinusitis : 400 mg once daily 7-10 days. Acute bacterial exacerbation of chronic bronchitis : 400 mg once daily 5-10 days. Always follow your doctor's instructions.
What are the side effects of Macflox?
Common side effects of Macflox include nausea, vomiting, diarrhea, headache and dizziness.
Is Macflox safe in pregnancy?
US FDA pregnancy category C. Moxifloxacin is not recommended during pregnancy & lactation. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.