Indications
Mebantrin is indicated for the treatment of threadworms, whipworms, roundworms and hookworms.
Pharmacology
Mebendazole is a synthetic broad-spectrum anthelmintic that is active against most nematodes and some other worms. Mebendazole is principally used in the treatment of intestinal nematode infection. Mebendazole inhibits the formation of the worms' microtubules and causes the worms' glucose depletion. After oral administration about 2-10% of oral dose is absorbed from Gl tract and peak plasma concentration occurs within 30 minutes to 7 hours. Mebendazole is highly bound to plasma protein. Elimination half-life is 2.8 to 9 hours.
Dosage and administration
Adult and Child over 2 years-
Threadworms : 100 mg or 1 teaspoonful: Single dose.
Whipworms, Roundworms, Hookworms : 100 mg or 1 teaspoonful: Twice daily for 3 days.
If reinfection occurs the second dose may be needed after 2 weeks.
Interactions
Preliminary evidence suggests that cimetidine inhibits Mebantrin metabolism and may result in an increase in plasma concentration.
Contraindications
Mebendazole is contraindicated in patients with known hypersensitivity to Mebendazole, or to any component of the formulation.
Side effects
Gastrointestinal: Transient symptoms of abdominal pain and diarrhoea in case of massive infection and expulsion of worms.
Hypersensitivity: Rash, urticaria and angioedema have been observed on rare occasions.
Central Nervous System: Very rare cases of convulsions have been reported.
Haematologic: Neutropenia and agranulocytosis.
Pregnancy and lactation
Mebendazole is not recommended in pregnant women. It is not known whether mebendazole is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when it is administered to a nursing mother.
Precautions and warnings
General : Periodic assessment of organ system functions, including haematopoietic and hepatic, is advisable during prolonged therapy. Information for Patients : Patients should be informed of the potential risk to the foetus in women taking Mebantrin during pregnancy, especially during the first trimester. Patients should also be informed that cleanliness is important to prevent reinfection & transmission of the infection.
Overdose
In the event of accidental overdosage, gastrointestinal complaints lasting up to a few hours may occur. Vomiting and purging should be induced.
Storage
Store in a cool (Below 25°C temperature) and dry place, protected from light. Keep out of the reach of children.
Similar brands of Mebendazole
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Seemox | Seema Pharmaceuticals Ltd. | Oral Suspension | 100 mg/5 ml | Not listed |
| 2 | Solas | Opsonin Pharma Ltd. | Oral Suspension | 100 mg/5 ml | Not listed |
| 3 | Helben | Ad-din Pharmaceuticals Ltd. | Oral Suspension | 100 mg/5 ml | Not listed |
| 4 | Helmox | Rephco Pharmaceuticals Ltd. | Oral Suspension | 100 mg/5 ml | Not listed |
| 5 | Panamox | Jayson Pharmaceutical Ltd. | Oral Suspension | 100 mg/5 ml | Not listed |
| 6 | Mebrex | Medimet Pharmaceuticals Ltd. | Oral Suspension | 100 mg/5 ml | Not listed |
| 7 | Mebendox | Indo Bangla Pharmaceutical | Oral Suspension | 100 mg/5 ml | Not listed |
| 8 | Promex | Apollo Pharmaceutical Ltd. | Chewable Tablet | 100 mg | ৳ 0.71per unit |
| 9 | Mebendox | Indo Bangla Pharmaceutical | Chewable Tablet | 100 mg | ৳ 0.74per unit |
| 10 | Mebrex | Medimet Pharmaceuticals Ltd. | Chewable Tablet | 100 mg | ৳ 0.74per unit |
| 11 | Seemox | Seema Pharmaceuticals Ltd. | Chewable Tablet | 100 mg | ৳ 0.74per unit |
| 12 | Vermizol | Zenith Pharmaceuticals Ltd. | Chewable Tablet | 100 mg | ৳ 0.74per unit |
| 13 | Mebantrin | Pharmadesh Laboratories Ltd. | Chewable Tablet | 100 mg | ৳ 0.75per unit |
| 14 | Solagen | Biogen Pharmaceuticals Ltd. | Chewable Tablet | 100 mg | ৳ 1.00per unit |
| 15 | Panamox | Jayson Pharmaceutical Ltd. | Chewable Tablet | 100 mg | ৳ 1.00per unit |
| 16 | Solas | Opsonin Pharma Ltd. | Chewable Tablet | 100 mg | ৳ 1.15per unit |
Common questions
What is Mebantrin used for?
Mebantrin is indicated for the treatment of threadworms, whipworms, roundworms and hookworms.
What is the generic name of Mebantrin?
Mebantrin contains Mebendazole, which belongs to the group: Anthelmintic.
Who makes Mebantrin?
Mebantrin is marketed in Bangladesh by Pharmadesh Laboratories Ltd..
How is Mebantrin taken?
Adult and Child over 2 years- Threadworms : 100 mg or 1 teaspoonful: Single dose. Whipworms, Roundworms, Hookworms : 100 mg or 1 teaspoonful: Twice daily for 3 days. Always follow your doctor's instructions.
What are the side effects of Mebantrin?
Gastrointestinal: Transient symptoms of abdominal pain and diarrhoea in case of massive infection and expulsion of worms. Hypersensitivity: Rash, urticaria and angioedema have been observed on rare occasions.
Is Mebantrin safe in pregnancy?
Mebendazole is not recommended in pregnant women. It is not known whether mebendazole is excreted in human milk. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.