Naftin

Naftin cream is an allylamine antifungal indicated for the treatment of interdigital tinea pedis, tinea cruris, and tinea corporis caused by the organism Trichophyton Rubrum.

The exact mechanism of action against fungi is not known, Naftifine Hydrochloride appears to interfere with sterol biosynthesis by inhibiting the enzyme squalene 2, 3-epoxidase. This inhibition of enzyme activity results in decreased amounts of sterols, especially ergosterol and a corresponding accumulation of squalene in the cells.

Apply a thin layer of Naftifine Hydrochloride Cream once-daily to the affected areas plus half inch margin of healthy surrounding skin for 2 weeks or as directed by the physician. Use in Children and Adolescents: The safety and effectiveness of Naftifine Hydrochloride have been established in the age group of 12-17 years with interdigital tinea pedis and tinea cruris.

No information is available.

The most common adverse reaction (≥1%) is pruritus.

Pregnancy Category B. There are no adequate and well-controlled studies of Naftifine Cream in pregnant women. Because animal reproduction studies are not always predictive of human response, Naftifine Cream should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Naftifine Cream is administered to a nursing woman.

If irritation or sensitivity develops with the use of Naftin Cream, treatment should be discontinued.

An overdose of Naftin topical is not expected to be dangerous.

Store below 30°C, away from light and in a dry place. Keep out of the reach of children.