Indications
Nispore eye drop is indicated in the treatment of fungal corneal ulcers/ keratitis.
Pharmacology
Fluconazole eye drop is a topical ophthalmic solution containing Fluconazole (a bis-triazole derivative) having established therapeutic activity against superficial ocular fungal infections. Fluconazole is fungistatic in action. The drug inhibits cytochrome P-450 14-alfa demethylase in susceptible fungi which leads to alteration of cellular membrane resulting in increased membrane permeability, leakage of essential elements and impaired uptake of precursor molecules to DNA.
Dosage and administration
Instill 1 drop to be instilled into the affected eye(s) 5 times daily.
Interactions
Nispore can alter pharmacokinetics of certain drugs undergoing hepatic metabolism.
Contraindications
The drug is contraindicated in patients with hypersensitivity to azoles.
Side effects
Nispore is generally well tolerated. Eosinophillia has been reported in some patients.
Pregnancy and lactation
There are no adequate and well-controlled studies in pregnant women. Fluconazole should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nursing mother should not be given as the drug is excreted in breast milk in concentration similar to plasma.
Precautions and warnings
Use of Nispore may result in overgrowth of non-susceptible strains of candida other than Candida albicans
Storage
Keep out of the reach of children. Store in a cool, dry place, away from heat and direct light. Do not use more than 4 weeks after opening the bottle.
Similar brands of Fluconazole (Ophthalmic)
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Naz | Reman Drug Laboratories Ltd. | Ophthalmic Solution | 0.3% | Not listed |
Common questions
What is Nispore used for?
Nispore eye drop is indicated in the treatment of fungal corneal ulcers/ keratitis.
What is the generic name of Nispore?
Nispore contains Fluconazole (Ophthalmic), which belongs to the group: Ophthalmic Anti-fungal Products.
Who makes Nispore?
Nispore is marketed in Bangladesh by Incepta Pharmaceuticals Ltd..
How is Nispore taken?
Instill 1 drop to be instilled into the affected eye(s) 5 times daily. Always follow your doctor's instructions.
What are the side effects of Nispore?
Nispore is generally well tolerated. Eosinophillia has been reported in some patients.
Is Nispore safe in pregnancy?
There are no adequate and well-controlled studies in pregnant women. Fluconazole should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.