MEDICINE

Nytkof

(10 mg+30 mg+1.25 mg)/5 ml Syrup · Dextromethorphan + Pseudoephedrine + Triprolidine

Indications

Nytkof temporarily relieves these symptoms due to common cold, hay fever (allergic rhinitis) or other upper respiratory allergies:

  • Non-productive cough due to minor throat or bronchial irritation
  • Runny Nose
  • Sneezing
  • Itching of the nose or throat
  • Itchy & watery eyes
  • Nasal congestion

Pharmacology

This preparation is a mixture of antitussive, decongestant and antihistamine agent. Dextromethorphan is a safe, effective, non-narcotic antitussive agent which has a central action on the cough centre in the medulla. Although structurally related to Morphine, it has no analgesic and habit forming properties and in general it has little sedative activity. Phenylephrine is a decongestant that shrinks blood vessels in the nasal passage. Phenylephrine is used for the temporary relief of stuffy nose, sinus, and ear symptoms caused by the common cold, flu, allergies, sinusitis & bronchitis. This medication works by decreasing swelling in the nose and ears, thereby lessening discomfort and making it easier to breathe. Triprolidine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, watery eyes, itchy eyes/nose/throat/skin, cough, runny nose, and sneezing. It is a potent competitive histamine H1-receptor antagonist of the pyrrolidine class with mild central nervous system depressant properties which may cause drowsiness. By antagonizing another natural substance acetylcholine, it helps dry up some body fluids to relieve symptoms such as watery eyes and runny nose.

Dosage and administration

Adults & Children over 12 years : 1 teaspoonful (5 ml) 4 times a day every 4 hours interval. 6-12 years : 1/2 teaspoonful 4 times a day every 4 hours interval. Use in children and adolescents : A physician's advice should be obtained before administering this combination to children less than 6 years.

Interactions

Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking isocarboxazid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, or tranylcypromine during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication.

Contraindications

It should be avoided in patients with liver disease or asthmatic patients and is contraindicated in patients taking monoamine oxidase inhibitors or within 2 weeks from stopping such treatment

Side effects

It may cause drowsiness and constipation. Other side effects that may occur include GIT discomfort. No apparent evidence of physical dependence of the morphine type.

Pregnancy and lactation

There are no specific data on use of this combination during pregnancy & lactation.

Precautions and warnings

Nytkof may cause drowsiness. If affected, do not drive motor vehicle or operate machinery. Avoid alcoholic drink while on this medication. Use with caution in patients with epilepsy, prostatic hypertrophy, glaucoma, hepatic disease, hypertension, heart disease, diabetes, hyperthyroidism. If symptoms do not improve within one week or accompanied with high fever, consult a physician before continuing use.

Overdose

In cases of over dosage, hospital admission is strongly advised. Over dosage may produce respiratory depression, paranoid psychosis, delusions, hallucinations and convulsion.

Storage

Store in a cool and dry place (below 30°C temperature), away from light. Keep out of the reach of children.

Similar brands of Dextromethorphan + Pseudoephedrine + Triprolidine

Brands of Dextromethorphan + Pseudoephedrine + Triprolidine
#BrandCompanyFormStrengthPrice
1Delkof PlusPopular Pharmaceuticals Ltd.Syrup(10 mg+30 mg+1.25 mg)/5 mlNot listed
2NilkofAmbee Pharmaceuticals Ltd.Syrup(10 mg+30 mg+1.25 mg)/5 mlNot listed
3CofnoAlco Pharma Ltd.Syrup(10 mg+30 mg+1.25 mg)/5 mlNot listed
4DexdinSomatec Pharmaceuticals Ltd.Syrup(10 mg+30 mg+1.25 mg)/5 mlNot listed
5A-CofACME Laboratories Ltd.Syrup(10 mg+30 mg+1.25 mg)/5 mlNot listed
6DecoffHudson Pharmaceuticals Ltd.Syrup(10 mg+30 mg+1.25 mg)/5 mlNot listed
7DexitraNovo Healthcare and Pharma Ltd.Syrup(10 mg+30 mg+1.25 mg)/5 mlNot listed
8DexpotenEskayef Pharmaceuticals Ltd.Syrup(10 mg+30 mg+1.25 mg)/5 mlNot listed
9DextropEdruc LimitedSyrup(10 mg+30 mg+1.25 mg)/5 mlNot listed
10FreecofAristopharma Ltd.Syrup(10 mg+30 mg+1.25 mg)/5 mlNot listed
11Koftex-DAmico Laboratories Ltd.Syrup(10 mg+30 mg+1.25 mg)/5 mlNot listed
12OfkofSquare Pharmaceuticals PLCSyrup(10 mg+30 mg+1.25 mg)/5 mlNot listed
See every brand of Dextromethorphan + Pseudoephedrine + Triprolidine →

Common questions

What is Nytkof used for?

Nytkof temporarily relieves these symptoms due to common cold, hay fever (allergic rhinitis) or other upper respiratory allergies: Non-productive cough due to minor throat or bronchial irritation Runny Nose Sneezing Itching of the nose or throat Itchy & watery eyes Nasal congestion

What is the generic name of Nytkof?

Nytkof contains Dextromethorphan + Pseudoephedrine + Triprolidine, which belongs to the group: Combined cough suppressants.

Who makes Nytkof?

Nytkof is marketed in Bangladesh by Beacon Pharmaceuticals PLC.

How is Nytkof taken?

Adults & Children over 12 years : 1 teaspoonful (5 ml) 4 times a day every 4 hours interval. 6-12 years : 1/2 teaspoonful 4 times a day every 4 hours interval. Always follow your doctor's instructions.

What are the side effects of Nytkof?

It may cause drowsiness and constipation. Other side effects that may occur include GIT discomfort.

Is Nytkof safe in pregnancy?

There are no specific data on use of this combination during pregnancy & lactation. Ask your doctor before using it while pregnant or breastfeeding.

This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.