Indications
Opsophenicol is indicated for the treatment of ocular infections involving the conjunctiva and/or cornea caused by Opsophenicol-susceptible organisms. Such as Staphylococcus aureus, Streptococcus pneumoniae, E.coli, H. influenzae, Klebsiella/Enterobacter spp, Moraxella lacunata, and Neisseria species.
Pharmacology
Chloramphenicol is a broad-spectrum bacteriostatic antibiotic which acts through the inhibition of bacterial protein synthesis by interfering with the transfer of activated amino acids from soluble RNA to ribosomes.
Dosage and administration
Adult and Children : Instill 1 or 2 drops in the conjunctival sac 4-6 times per day for the first 72 hours and then every 4 hours thereafter. Treatment should be continued for approximately 7 days, but should not be continued for more than 3 weeks without re-evaluation by the physician.
Interactions
Chymotrypsin may be inhibited if given simultaneously with Opsophenicol.
Contraindications
It is contraindicated in individuals with a history of hypersensitivity to Chloramphenicol or any ingredients of the preparation.
Side effects
The systemic adverse reaction has not been observed within short-term topical use of Opsophenicol. The most frequently reported adverse reactions have been burning, stinging, conjunctival hyperemia, blood dyscrasia, allergic or inflammatory reactions, vesicular and maculopapular dermatitis.
Pregnancy and lactation
Safety for use in pregnancy and lactation has not been established. Therefore, use only when considered essential by the physicians.
Precautions and warnings
Opsophenicol ophthalmic solution should never be given for minor infections or for prophylaxis. Repeated course and prolonged treatment should be avoided. Blood dyscrasias (granulocytopenia, thrombocytopenia and moderate anaemia) may occur after prolonged ophthalmic use.
Overdose
Accidental ingestion of the medicine is unlikely to cause any toxicity due to low content of antibiotic.
Storage
Store in a cool (between 2°C-8°C) and dry place, protect from light, keep out of reach of children. Do not touch the dropper tip to the surface since this may contaminate the solution. Do not use after 30 days of the first opening.
Similar brands of Chloramphenicol (Ophthalmic)
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Optichlor | Jayson Pharmaceutical Ltd. | Ophthalmic Ointment | 1% | Not listed |
| 2 | Optaphenicol | Reman Drug Laboratories Ltd. | Ophthalmic Ointment | 1% | Not listed |
| 3 | Cloram | The IBN SINA Pharmaceutical PLC | Ophthalmic Ointment | 1% | Not listed |
| 4 | Supraphen | Gaco Pharmaceuticals Ltd. | Ophthalmic Ointment | 1% | Not listed |
| 5 | Conicol | Opsonin Pharma Ltd. | Ophthalmic Ointment | 1% | Not listed |
| 6 | Chlorphen | Nipa Pharmaceuticals Ltd. | Ophthalmic Ointment | 1% | Not listed |
| 7 | Aristophen | Aristopharma Ltd. | Ophthalmic Ointment | 1% | Not listed |
| 8 | Opsophenicol | OSL Pharma Limited | Ophthalmic Solution | 0.5% | Not listed |
| 9 | Optabac | Popular Pharmaceuticals Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 10 | Optaphenicol | Reman Drug Laboratories Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 11 | Opthacol | Drug International Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 12 | Optichlor | Jayson Pharmaceutical Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 13 | Opticol | Asiatic Laboratories Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 14 | Supraphen | Gaco Pharmaceuticals Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 15 | Eyephen | Healthcare Pharmaceuticals Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 16 | Chemophenicol | Chemist Laboratories Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 17 | Ocubac | Apex Pharma Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 18 | Ocuclor | General Pharmaceuticals Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 19 | Ocuram | Navana Pharmaceuticals Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 20 | Ocutrex | Beximco Pharmaceuticals Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 21 | Ramphen | Kemiko Pharmaceuticals Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 22 | Varen | Monicopharma Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 23 | Chlorovis | Biopharma Limited | Ophthalmic Solution | 0.5% | Not listed |
| 24 | Glophen | Globe Pharmaceuticals Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 25 | Chlorphen | Nipa Pharmaceuticals Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 26 | SQ-Mycetin | Square Pharmaceuticals PLC | Ophthalmic Solution | 0.5% | Not listed |
| 27 | Conicol | Opsonin Pharma Ltd. | Ophthalmic Solution | 0.5% | Not listed |
| 28 | Supraphen | Gaco Pharmaceuticals Ltd. | Ophthalmic Solution | 10% | Not listed |
| 29 | Supraphen | Gaco Pharmaceuticals Ltd. | Ophthalmic Solution | 5% | Not listed |
| 30 | Nidependiol | Pacific Pharmaceuticals Ltd. | Ophthalmic Solution | 0.5% | Not listed |
Common questions
What is Opsophenicol used for?
Opsophenicol is indicated for the treatment of ocular infections involving the conjunctiva and/or cornea caused by Opsophenicol-susceptible organisms. coli, H.
What is the generic name of Opsophenicol?
Opsophenicol contains Chloramphenicol (Ophthalmic), which belongs to the group: Anti-infectives & antiseptics, Macrolides.
Who makes Opsophenicol?
Opsophenicol is marketed in Bangladesh by OSL Pharma Limited.
How is Opsophenicol taken?
Adult and Children : Instill 1 or 2 drops in the conjunctival sac 4-6 times per day for the first 72 hours and then every 4 hours thereafter. Treatment should be continued for approximately 7 days, but should not be continued for more than 3 weeks without re-evaluation by the physician. Always follow your doctor's instructions.
What are the side effects of Opsophenicol?
The systemic adverse reaction has not been observed within short-term topical use of Opsophenicol. The most frequently reported adverse reactions have been burning, stinging, conjunctival hyperemia, blood dyscrasia, allergic or inflammatory reactions, vesicular and maculopapular dermatitis.
Is Opsophenicol safe in pregnancy?
Safety for use in pregnancy and lactation has not been established. Therefore, use only when considered essential by the physicians. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.