Indications
This is indicated to relieve symptoms of dyspepsia, heartburn, acid indigestion, sour stomach, gastroesophageal reflux and hiatal hernia. It is also prescribed in hyperacidity associated with peptic ulcers, gastritis and esophagitis. Magaldrate may be given to children if necessary. Also indicated for the relief of flatulence, abdominal distension and windy colic.
Pharmacology
This is a combination of magaldrate and simethicone. Magaldrate (magnesium aluminium compound i.e. Hydroxymagnesium Aluminate), which neutralizes gastric acid extraordinarily quickly without raising the pH above 5-6. It also decreases the activity of pepsin in gastric secretion. Besides this, simethicone, the another component of Marlox Plus, enables the gas buble to coalesce and give relief from flatulence.
Dosage and administration
Tablet : 1-4 chewable tablets, 20 to 60 minutes after meals and at bedtime, or as directed by the physician. Suspension : 2-4 teaspoonfuls (10-20 ml) of suspension, 20 to 60 minutes after meals and at bed time, or as directed by the physician.
Interactions
It should not be used in patients taking any form of Tetracycline. The drug may cause reduced bio-availability or slower absorption of a number of drugs including propranolol, isoniazid, prednisolone and naproxen.
Contraindications
Magaldrate is contraindicated in patients with known hypersensitivity to magnesium and aluminium. It is also contraindicated in patients with impaired renal functions.
Side effects
Gastrointestinal side-effects are uncommon. Occasionally, if excessive amount is consumed, diarrhea, constipation or regurgitation may occur.
Pregnancy and lactation
Magaldrate may be used in pregnancy if indicated however one should avoid excessive dosage. Magaldrate may pass into breast milk but has not been reported to cause problem in nursing babies.
Precautions and warnings
Care should be taken in decreased kidney function, hypophosphataemia and weak people.
Overdose
Over dosage with this formulation is a rare case.
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Similar brands of Magaldrate + Simethicone
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Marlox Plus | Incepta Pharmaceuticals Ltd. | Chewable Tablet | 480 mg+20 mg | ৳ 3.00per unit |
| 2 | Gastid | Eskayef Pharmaceuticals Ltd. | Chewable Tablet | 480 mg+20 mg | ৳ 3.00per unit |
| 3 | Magalrat Plus | The IBN SINA Pharmaceutical PLC | Chewable Tablet | 480 mg+20 mg | ৳ 3.00per unit |
| 4 | Magacil Plus | Opsonin Pharma Ltd. | Chewable Tablet | 480 mg+20 mg | ৳ 3.01per unit |
| 5 | Novelta | Orion Pharma Ltd. | Chewable Tablet | 480 mg+20 mg | ৳ 3.01per unit |
| 6 | Maganta Plus | Square Pharmaceuticals PLC | Chewable Tablet | 480 mg+20 mg | ৳ 3.01per unit |
| 7 | Gastid | Eskayef Pharmaceuticals Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 8 | Maganta Plus | Square Pharmaceuticals PLC | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 9 | Novelta | Orion Pharma Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 10 | Avlocid MS | ACI Limited | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 11 | Magacil Plus | Opsonin Pharma Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 12 | Magalcon Plus | Ethical Drugs Limited | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 13 | Magalrat Plus | The IBN SINA Pharmaceutical PLC | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 14 | Magaplus-X | Kemiko Pharmaceuticals Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 15 | Marlox Plus | Incepta Pharmaceuticals Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 16 | Megasim | Medicon Pharmaceuticals Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 17 | Oxecone-MS | ACME Laboratories Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 18 | Pepcon Plus | Leon Pharmaceuticals Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 19 | Maxicon | Aristopharma Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 20 | Nilcid | Novatek Pharmaceuticals Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 21 | Nygas | Team Pharmaceuticals Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 22 | Magasol | Globe Pharmaceuticals Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 23 | Maldrox | Drug International Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 24 | Simegal | Beacon Pharmaceuticals PLC | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 25 | Duocid | OSL Pharma Limited | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 26 | Mamet | Ad-din Pharmaceuticals Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 27 | Gastid M | Eskayef Pharmaceuticals Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 28 | Gastid S | Eskayef Pharmaceuticals Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
| 29 | Digecid | Beximco Pharmaceuticals Ltd. | Oral Suspension | (480 mg+20 mg)/5 ml | Not listed |
Common questions
What is Pepcon Plus used for?
This is indicated to relieve symptoms of dyspepsia, heartburn, acid indigestion, sour stomach, gastroesophageal reflux and hiatal hernia. It is also prescribed in hyperacidity associated with peptic ulcers, gastritis and esophagitis.
What is the generic name of Pepcon Plus?
Pepcon Plus contains Magaldrate + Simethicone, which belongs to the group: Antacids, Anti-dyspeptic/Carminatives.
Who makes Pepcon Plus?
Pepcon Plus is marketed in Bangladesh by Leon Pharmaceuticals Ltd..
How much does Pepcon Plus 480 mg+20 mg cost?
The listed price is ৳ 3.00 per unit and ৳ 30.00 per strip. Prices can change, so check with your pharmacy.
How is Pepcon Plus taken?
Tablet : 1-4 chewable tablets, 20 to 60 minutes after meals and at bedtime, or as directed by the physician. Suspension : 2-4 teaspoonfuls (10-20 ml) of suspension, 20 to 60 minutes after meals and at bed time, or as directed by the physician. Always follow your doctor's instructions.
What are the side effects of Pepcon Plus?
Gastrointestinal side-effects are uncommon. Occasionally, if excessive amount is consumed, diarrhea, constipation or regurgitation may occur.
Is Pepcon Plus safe in pregnancy?
Magaldrate may be used in pregnancy if indicated however one should avoid excessive dosage. Magaldrate may pass into breast milk but has not been reported to cause problem in nursing babies. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.