Prosma

Prosma is indicated for the treatment and prevention of signs and symptoms of seasonal allergic conjunctivitis.

Ketotifen is a potent anti-allergic substance possessing a powerful and sustained non-competitive histamine (H1) receptor blocking property. Ketotifen inhibits the release of mediators from cells responsible for type I allergic reactions. Ketotifen also stabilizes mast cells, decreases chemotaxis, activation and degranulation of eosinophils.

Adults and children over 3 years of age : 1 drop Ketotifen eye drop into the conjunctival sac of the affected eye(s) twice a day or as directed by the physician. Children below 3 years of age : Not recommended.

If Prosma eye drops is used concomitantly with other eye medications there must be an interval of at least 5 minutes between the two medications.

Hypersensitivity to Ketotifen or any of the components

Generally side effects of Prosma are localized ocular toxicity and hypersensitivity such as burning or stinging, punctate corneal epithelial erosion, dry eyes, eyelid disorder, photophobia, keratitis, lacrimation etc. Systemic side effects are very rare, there may be headache, urticaria, dry mouth and allergic reaction.

There are no adequate and well-controlled studies about the use of Ketotifen eye drops in pregnant women. Systemic levels after ocular administration are much lower than oral use. Caution should be exercised when prescribing to pregnant women. Topical administration to humans is unlikely to produce detectable quantities in breast milk. Ketomar eye drops can be used during lactation.

The formulation of Prosma eye drops contains benzalkonium chloride as a preservative, which may be deposited in soft contact lenses; therefore Prosma eye drops should not be instilled while the patient is wearing contact lenses. The lenses should be removed before application of the drops and not reinserted earlier than 15 minutes after use.

Signs and symptoms of an overdose may be similar to the reactions described above under side effects.

Close the bottle immediately after use. Should not use after 4 weeks of opening. keep in a cool and dry place away from light. Keep all the medicine out of reach of children.