Indications
Pvast is indicated for the symptomatic treatment of:
Seasonal and perennial allergic rhinitis.
Chronic idiopathic urticaria.
Pharmacology
Ebastine is a long-acting and selective H1-histamine receptor antagonist. After repeated administration, inhibition of peripheral receptors remains at a constant level. Ebastine is rapidly absorbed and undergoes extensive first-pass metabolism following oral administration. Ebastine is almost totally converted to the pharmacologically active acid metabolite, carebastine.
Dosage and administration
Tablet:
Adults (more than 12 years of age) : 10 mg (one tablet) once daily.
Children (6-12 years of age) : 5 mg (half tablet) once daily.
Syrup:
Children (2-5 years of age) : 2.5 ml once daily (upto 5 ml in severe cases such as Perennial Allergic Rhinitis).
Children (6-12 years of age) : 5 ml once daily (upto 10 ml in severe cases such as Perennial Allergic Rhinitis).
Ebastine may be taken with or without food.
Interactions
Pvast in combination with either ketoconazole or erythromycin increases in plasma level of Pvast and prolonged QTc interval. Pvast does not interact with the pharmacokinetics of theophylline, warfarin, cimetidine, diazepam or alcohol. The sedation effect of alcohol and diazepam may be enhanced.
Contraindications
Patients with a known hypersensitivity to Ebastine or any of its ingredients.
Side effects
The most common side-effects are headache, dry mouth and drowsiness. Less commonly reported side effects include abdominal pain, dyspepsia, nausea and insomnia.
Overdose
No clinically meaningful signs or symptoms were observed up to 100 mg given once daily. There is no specific antidote for Pvast. In case of accidental overdoses, gastric lavage, monitoring of vital functions including ECG and symptomatic treatment should be carried out.
Storage
Store below 30°C at a cool and dry place, away from light. Keep out of reach of children
Similar brands of Ebastine
Common questions
What is Pvast used for?
Pvast is indicated for the symptomatic treatment of: Seasonal and perennial allergic rhinitis. Chronic idiopathic urticaria.
What is the generic name of Pvast?
Pvast contains Ebastine, which belongs to the group: Anti-histamine.
Who makes Pvast?
Pvast is marketed in Bangladesh by Monicopharma Ltd..
How is Pvast taken?
Tablet: Adults (more than 12 years of age) : 10 mg (one tablet) once daily. Children (6-12 years of age) : 5 mg (half tablet) once daily. Always follow your doctor's instructions.
What are the side effects of Pvast?
The most common side-effects are headache, dry mouth and drowsiness. Less commonly reported side effects include abdominal pain, dyspepsia, nausea and insomnia.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.