Indications
Tie is an antispasmodic drug that reduces muscles spasm of the intestine, biliary system, bladder and uterus. It is used in symptomatic treatment of pain related to functional disorders of the digestive tract and biliary system. It is also indicated for the treatment of spasm and pain in urological and gynaecological diseases.
Pharmacology
Tiemonium Methylsulphate a competitive antagonist of Acetylcholine, Histamine and strengthens of calcium bond with membrane phospholipids and proteins. Thus inhibits intracellular contractile protein of visceral cell which causes inhibition of visceral spasm and pain.
Dosage and administration
Tablet/Syrup -
Adult: usual dose is 2-6 tablets or 3-9 teaspoonfuls syrup daily in divided doses.
Children: 3 ml/kg or 6 mg/kg body weight daily in divided doses.
Injection : 1 injection 3 times daily, through Intravenous route slowly or Intramuscular route. Suppository : 20 mg suppository two or three times daily, through rectal route.
Interactions
Tie methylsulphate tablet should not be used with other drugs without prior consult of a registered physician to avoid possible drug interaction.
Contraindications
It should not be used in urethroprostatic disorder involving a risk of urine retension. It is contraindicated in patient with having risk of angle closure glaucoma.
Side effects
Tie Methylsulphate may have the risk of hypotension & tachycardia in certain individuals.
Pregnancy and lactation
The results of animal studies of Tiemonium Methylsulphate did not reveal any teratogenic effects; no deformities have been reported up till now with normal use. In absence of sufficient data, prudence should be the rule for nursing mothers although no problems have been reported with normal use.
Precautions and warnings
Caution should be taken during treatment of patients with disorders of the prostate. Caution should also be taken in case of chronic bronchitis, coronary insufficiency, ambient hyperthermia, renal & hepatic insufficiency. The risks of visual disturbances can make it dangerous to drive or use machines.
Overdose
There is not available data regarding the overdose of Tie methylsulphate tablet.
Storage
Keep in a dry place, away from light and heat. Keep out of the reach of children.
Similar brands of Tiemonium Methylsulfate
Common questions
What is Tie used for?
Tie is an antispasmodic drug that reduces muscles spasm of the intestine, biliary system, bladder and uterus. It is used in symptomatic treatment of pain related to functional disorders of the digestive tract and biliary system.
What is the generic name of Tie?
Tie contains Tiemonium Methylsulfate, which belongs to the group: Anticholinergics.
Who makes Tie?
Tie is marketed in Bangladesh by One Pharma Ltd..
How much does Tie 50 mg cost?
The listed price is ৳ 8.00 per unit and ৳ 80.00 per strip. Prices can change, so check with your pharmacy.
How is Tie taken?
Tablet/Syrup - Adult: usual dose is 2-6 tablets or 3-9 teaspoonfuls syrup daily in divided doses. Children: 3 ml/kg or 6 mg/kg body weight daily in divided doses. Always follow your doctor's instructions.
What are the side effects of Tie?
Tie Methylsulphate may have the risk of hypotension & tachycardia in certain individuals.
Is Tie safe in pregnancy?
The results of animal studies of Tiemonium Methylsulphate did not reveal any teratogenic effects; no deformities have been reported up till now with normal use. In absence of sufficient data, prudence should be the rule for nursing mothers although no problems have been reported with normal use. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.