Indications
Tritin is indicated for-
Treatment and relief of symptoms associated with Irritable Bowel Syndrome (IBS).
Postoperative paralytic ileus in order to accelerate the resumption of the intestinal transit following abdominal surgery.
Pharmacology
Trimebutine Maleate is a noncompetitive spasmolytic agent.lt possesses moderate opiate receptor affinity and has marked anti-serotonin activity especially on 'mu' receptors. It induces regulation of spontaneous activity and increases synchronization between electrophysiological spikes and contractions in isolated guinea pig strips of colon and ileum. However, it does not alter normal motility, but regulates abnormal intestinal activity.
Dosage and administration
Children over 12 years and Adults: 1 or 2 tablets, 3 times/day before meals.
Interactions
No other drug interactions have been observed during clinical trials or otherwise reported.
Contraindications
Patients with known hypersensitivity to Trimebutine Maleate or any excipient.
Side effects
Tritin is generally well tolerated. The infrequently reported adverse effects are as follows: dry mouth, foul taste, diarrhea, dyspepsia, epigastric pain, nausea, constipation, drowsiness, fatigue, dizziness, hot/cold sensations, headache etc.
Pregnancy and lactation
Although teratological studies have not shown any drug related adverse effects on the course and outcome of pregnancy, the use of Trimebutine Maleate in pregnant women is not recommended. It is not known ifTrimebutine Maleate passes into breast milk. This medication should be used while breast feeding only if the potential benefits outweigh risks to the nursing infants.
Precautions and warnings
Elderly, pregnancy and lactation
Overdose
No evidence of overdosage have been reported to date. However, if overdosage should occur following oral administration, gastric lavage is recommended. Treatment should be made according to the symptoms observed.
Storage
Store in a cool and dry place,away from light and moisture.
Similar brands of Trimebutine Maleate
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Trimotil | Incepta Pharmaceuticals Ltd. | Tablet | 100 mg | ৳ 5.00per unit |
| 2 | Timotor | Square Pharmaceuticals PLC | Tablet | 100 mg | ৳ 6.00per unit |
Common questions
What is Tritin used for?
Tritin is indicated for- Treatment and relief of symptoms associated with Irritable Bowel Syndrome (IBS). Postoperative paralytic ileus in order to accelerate the resumption of the intestinal transit following abdominal surgery.
What is the generic name of Tritin?
Tritin contains Trimebutine Maleate, which belongs to the group: Anticholinergics.
Who makes Tritin?
Tritin is marketed in Bangladesh by Renata PLC.
How much does Tritin 100 mg cost?
The listed price is ৳ 5.00 per unit and ৳ 50.00 per strip. Prices can change, so check with your pharmacy.
How is Tritin taken?
Children over 12 years and Adults: 1 or 2 tablets, 3 times/day before meals. Always follow your doctor's instructions.
What are the side effects of Tritin?
Tritin is generally well tolerated. The infrequently reported adverse effects are as follows: dry mouth, foul taste, diarrhea, dyspepsia, epigastric pain, nausea, constipation, drowsiness, fatigue, dizziness, hot/cold sensations, headache etc.
Is Tritin safe in pregnancy?
Although teratological studies have not shown any drug related adverse effects on the course and outcome of pregnancy, the use of Trimebutine Maleate in pregnant women is not recommended. It is not known ifTrimebutine Maleate passes into breast milk. Ask your doctor before using it while pregnant or breastfeeding.
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.