GENERIC
Levamisole Hydrochloride
Indications
- G-Levamizole is indicated in-
- Ascariasis
- Hookworm infections
Effective against Enterobius vermi-cularis, Trichuris trichiura, Strongyloide stercoralis and Trichostrongylus colubriformis etc.
Pharmacology
Levamisole is the active laevo-isomer of tetramisole. It works by paralysing susceptible intestinal worms which are then excreted from the intestines. Levamisole also enhances cellular immune responses in humans.
Dosage and administration
The following doses of Levamisole are given as a single administration, preferably after a light meal.
Age 1-4 year : 1 Tablets or 5 ml Syrup
Age 5-15 year : 2 Tablets or 10 ml Syrup
Age 16 year and over : 3 Tablets or 15 ml Syrup
In cases of severe hookworm infection it is suggested that a second standard dose be given one or seven days after the first, whichever timing is feasible.
Interactions
May increase toxicity of phenytoin. Increases bioavailability of ivermectin; decreases bioavailability of albendazole. Alcohol causes disulfiram-like reaction.
Contraindications
It is contraindicated in patients hypersensitive to Levamisole. Levamisole should not be given during pregnancy.
Side effects
Side effects are infrequent. They are usually mild and transient and include nausea, vomiting, abdominal pain, giddiness (dizziness) and headache. An encephalopathy like syndrome has been reported to have occurred in a few patients two or three weeks after treatment.
Pregnancy and lactation
Although studies in animals have shown that Levamisole produces no teratogenic effects, current medical practice requires that the benefits of any drug used during pregnancy should be weighed against the possible dangers.
Precautions and warnings
Effect on ability to drive or operate machinery : There is no evidence to suggest that G-Levamizole , used for anthelmintic purpose, will produce sedation. Mild and transient giddiness is an infrequent side-effect of treatment. No precautions are suggested concerning the ability to drive or operate machinery. In case of concurrent microfilaraemia transient fever may occur.
Storage
Keep all medicines out of reach of children. Store in a cool and dry place protected from light
Clinical information is taken from the most complete brand listing (G-Levamizole); it applies to the active ingredient.
Brands of Levamisole Hydrochloride
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 1 | Altrax | Alkad Laboratories | Syrup | 40 mg/5 ml | Not listed |
| 2 | Asitrax | Asiatic Laboratories Ltd. | Syrup | 40 mg/5 ml | Not listed |
| 3 | Atrex | Aztec Pharmaceuticals Ltd. | Syrup | 40 mg/5 ml | Not listed |
| 4 | Biotrex | Biopharma Limited | Syrup | 40 mg/5 ml | Not listed |
| 5 | Etrax | ACI Limited | Tablet | 40 mg | ৳ 1.00per unit |
| 6 | Etrax | ACI Limited | Syrup | 40 mg/5 ml | Not listed |
| 7 | G-Levamizole | Gonoshasthaya Pharma Ltd. | Syrup | 40 mg/5 ml | Not listed |
| 8 | Lemox | Bengal drugs Ltd. | Syrup | 40 mg/5 ml | Not listed |
| 9 | Levamin | Pharmadesh Laboratories Ltd. | Tablet | 40 mg | ৳ 0.46per unit |
| 10 | Levamin | Pharmadesh Laboratories Ltd. | Syrup | 40 mg/5 ml | Not listed |
| 11 | Levosol | Seema Pharmaceuticals Ltd. | Tablet | 40 mg | ৳ 0.45per unit |
| 12 | Levosol | Seema Pharmaceuticals Ltd. | Syrup | 40 mg/5 ml | Not listed |
| 13 | Neotrax | ACME Laboratories Ltd. | Syrup | 40 mg/5 ml | Not listed |
| 14 | Ovanil | Pharmik Laboratories Ltd. | Syrup | 40 mg/5 ml | Not listed |
| 15 | PTX | Pharmik Laboratories Ltd. | Syrup | 40 mg/5 ml | Not listed |
| 16 | Skytex | Skylab Pharmaceuticals Ltd. | Tablet | 40 mg | ৳ 0.45per unit |
| 17 | Skytex | Skylab Pharmaceuticals Ltd. | Syrup | 40 mg/5 ml | Not listed |
| 18 | Vermicom | Opsonin Pharma Ltd. | Syrup | 40 mg/5 ml | Not listed |
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.