GENERIC
Vitamin B1, B6 & B12
Indications
Neuro Vitamin is indicated where a deficiency of the relevant vitamins exists. It is indicated for the treatment of following diseases: Polyneuropathy of any origin such alcoholic or toxiconeuropathies as-diabetic, Neuritis, Neuralgia, Cervical Syndrome, Shoulder-arm syndrome, Lumbago, Sciatica, Myalgia, Intercostal neuralgia, Herpes Zoster, Trigeminal Neuralgia, Supportive treatment in facial paresis.
Pharmacology
Vitamin B1 converts carbohydrates, fatty acids and amino acids into energy, promotes healthy nerves, improves mood, strengthens the heart. Vitamin B6 forms RBCs, helps cells to make proteins, manufactures neurotransmitters e.g. serotonin and releases stored forms of energy, helps to prevent CVS diseases and stroke, helps to lift depression and eases insomnia. Vitamin B12 is essential for cell replication and important for RBC production, prevents anemia, helps to prevent depression, reduces nerve pain, numbness, tingling and lowers the risk of heart diseases. The vitamin ingredients are absorbed well in per oral reception. It is widely distributed to most tissues and appears in breast milk. Within the cell, thiamine is mostly present as diphosphate. Thiamine is not stored to any appreciable extent in the body and amounts in excess of the body’s requirements are excreted in the urine as unchanged thiamine or as metabolites. Pyridoxine, pyridoxal and pyridoxamine are readily absorbed from the GIT following oral administration and are converted to the active forms of pyridoxal phosphate an pyridoxamine phosphate. They are stored mainly in liver where there is oxidation to 4-pyridoxic acid and other inactive metabolites, which are excreted in urine. As the dose increases, proportionally greater amounts are excreted unchanged in the urine.
Dosage and administration
Tablet: 1-3 Tablets per day or as advised by the physician. Injection:
In severe (acute) cases : 1 injection daily until the acute symptoms subside or taken as advised by the physician.
In mild cases : 1 injection 2-3 times per week. Ampoules are preferably injected intramuscularly.
Use in children: There is no information on the use of this drug in children.
Interactions
No drug interaction has been reported yet.
Contraindications
Vitamin B1, Vitamin B6 and Vitamin B12 is contraindicated in patients on levodopa therapy, and in patients with hypersensitivity to any of the ingredients of the preparation.
Side effects
Generally well tolerated but allergic reactions may be observed in few cases.
Pregnancy and lactation
Oral tablet form is recommended but due to the presence of benzyl alcohol, injection is not recommended during pregnancy & lactation.
Precautions and warnings
Cyanocobalamin should not be given in patients with subacute degeneration of the spinal cord. Cyanocobalamin is not suitable form of vitamin B12 for the treatment of optic neuropathies associated with raised plasma concentrations of cyanocobalamin.
Overdose
No overdosage symptoms are to be expected in the recommended dosage. If there is known overdose then treatment is symptomatic & supportive.
Storage
Keep out of reach of children. Store in a cool (below 25°C temperature) and dry place, protected from light.
Clinical information is taken from the most complete brand listing (Neuro Vitamin); it applies to the active ingredient.
Brands of Vitamin B1, B6 & B12
| # | Brand | Company | Form | Strength | Price |
|---|---|---|---|---|---|
| 91 | Nuropa | Nipa Pharmaceuticals Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 7.00per unit |
| 92 | Nurowel | SMC Enterprise Ltd | Tablet | 100 mg+200 mg+200 mcg | ৳ 7.50per unit |
| 93 | N-Vit | MST Pharma | Tablet | 100 mg+200 mg+200 mcg | ৳ 5.00per unit |
| 94 | Orgabion | Novatek Pharmaceuticals Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 8.00per unit |
| 95 | OST | Central Pharmaceuticals Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 4.00per unit |
| 96 | Pacibion | Pacific Pharmaceuticals Ltd. | IM Injection | (100 mg+100 mg+1 mg)/3 ml | Not listed |
| 97 | Pacibion | Pacific Pharmaceuticals Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 9.00per unit |
| 98 | Povital | ACI Limited | IM Injection | (100 mg+100 mg+1 mg)/3 ml | Not listed |
| 99 | Povital | ACI Limited | Tablet | 100 mg+200 mg+200 mcg | ৳ 12.00per unit |
| 100 | Pristibion | Pristine Pharmaceuticals Ltd | Tablet | 100 mg+200 mg+200 mcg | ৳ 7.00per unit |
| 101 | Rebion | Rephco Pharmaceuticals Ltd. | IM Injection | (100 mg+100 mg+1 mg)/3 ml | Not listed |
| 102 | Rebion | Rephco Pharmaceuticals Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 8.33per unit |
| 103 | Rejubion | Beacon Pharmaceuticals PLC | IM Injection | (100 mg+100 mg+1 mg)/3 ml | Not listed |
| 104 | Rejubion | Beacon Pharmaceuticals PLC | Tablet | 100 mg+200 mg+200 mcg | ৳ 8.00per unit |
| 105 | Renep | Alco Pharma Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 8.00per unit |
| 106 | Renovit | Healthcare Pharmaceuticals Ltd. | IM Injection | (100 mg+100 mg+1 mg)/3 ml | Not listed |
| 107 | Renovit | Healthcare Pharmaceuticals Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 9.00per unit |
| 108 | SB-Neurec | Sunman-Birdem Pharma Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 8.00per unit |
| 109 | Serobion | Leon Pharmaceuticals Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 5.00per unit |
| 110 | Solbion | Eskayef Pharmaceuticals Ltd. | IM Injection | (100 mg+100 mg+1 mg)/3 ml | Not listed |
| 111 | Solbion | Eskayef Pharmaceuticals Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 10.00per unit |
| 112 | Spine-B | Novus Pharmaceuticals Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 4.00per unit |
| 113 | Supra-B | Drug International Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 9.00per unit |
| 114 | Temvit-N | Team Pharmaceuticals Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 9.00per unit |
| 115 | TPC | ACME Laboratories Ltd. | IM Injection | (100 mg+100 mg+1 mg)/3 ml | Not listed |
| 116 | TPC | ACME Laboratories Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 11.00per unit |
| 117 | Tri-B | The White Horse Pharmaceuticals Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 12.00per unit |
| 118 | Tribion | Globe Pharmaceuticals Ltd. | IM Injection | (100 mg+100 mg+1 mg)/3 ml | Not listed |
| 119 | Tribion | Globe Pharmaceuticals Ltd. | Tablet | 100 mg+200 mg+200 mcg | ৳ 9.00per unit |
| 120 | Trilin B | OSL Pharma Limited | IM Injection | (100 mg+100 mg+1 mg)/3 ml | Not listed |
This page is general information and is not medical advice. It does not replace a registered doctor, and it is not a prescription or a recommendation to use any medicine or test. Prices are listed prices and may change. Always follow the advice of your doctor or pharmacist.